The role of electrodeposition conditions in creating MnO2-based flexible non-enzymatic glucose sensors
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Rapid growth in diabetes morbidity compels researchers to develop an enzymeless alternative to currently used enzymatic glucose monitors. In relation to the target glucose electrooxidation reaction, a series of non-enzymatic flexible MnO 2 -based electrodes was fabricated by means of electrodeposition. The effect of electrodeposition parameters (solution temperature, concentration, deposition potential) on morphological and electrochemical characteristics of prepared MnO 2 samples was investigated. To exhibit practical prospects of electrodeposited MnO 2 electrocatalysts for the in vivo use, glucose electrooxidation was performed in an isotonic NaCl-based phosphate-buffered saline with pH 7.40 containing physiological (1–30 mM) glucose concentrations. A rotating ring-disk electrode was applied to reveal differences in the electrodeposition process under various conditions as well as to solidly establish potentials of MnO 2 cathodic dissolution and O 2 /Cl 2 evolution at pH 7.40. For the most active sensor electrode with pronounced MnO 2 surface architecture a linear square root concentration plot in the full physiological glucose range (1–30 mM) was demonstrated. Sensitivity values up to ca. 41.8 and 81.2 μA mM −0.5 cm −2 at 25 and 37 °C, respectively, were observed. Excellent reproducibility of the glucose oxidation current and good glucose selectivity of electrodeposited MnO 2 in relation to some common interferent substances (fructose, galactose, xylose, ribose, urea, lactic acid, acetone, ascorbic acid, paracetamol) were revealed. • Electrodeposition parameters strongly affect surface structure of a MnO 2 catalyst. • Electrodeposited MnO 2 provides reproducible glucose oxidation currents (pH 7.40). • Concentration plot shows linearity in a physiological glucose range (1–30 mM). • Sensitivity in the glucose oxidation achieves 27.9–41.8 μA mM −0.5 cm −2 geo at 25 °C. • MnO 2 affords glucose selectivity in the presence of physiological interferents.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it