THE ROLE OF INSULIN THERAPY REGIMENS AND THE COGNITIVE IMPAIRMENT
Bibliographic record
Abstract
Type 1 diabetes mellitus is characterized by a high level of glucose in the blood, requires lifelong insulin therapy and can cause acute and chronic complications in various organs and systems, including neurocognitive dysfunction.The purpose: to study the role of the insulin therapy regimen in the development of cognitive impairment in patients with type 1 diabetes mellitus.Materials and methods: 60 patients with type 1 diabetes mellitus were examined. All patients were divided into 2 groups: the 1st group received insulin with the help of multiple injections, the 2nd group - in the regime of pump insulin therapy. All patients underwent general clinical examination, testing of cognitive functions with the Montreal scale. The statistical analysis was carried out using the software package R-system.Results: the study revealed that in both groups with type 1 diabetes mellitus the decreased cognitive function was registered. It is shown that pump insulin therapy is associated with better performance of the tasks of the Montreal scale. In addition, it has been shown that more frequent episodes of diabetic ketoacidosis and high HbA1c are the main causes of cognitive impairment in this group of patients.Conclusion: cognitive disorders associated with acute and chronic hyperglycemia were verified in patients with type 1 diabetes. Pump insulin therapy improves cognitive functions.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.003 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.003 | 0.005 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".