Analise da eficácia da Combinação Cetamina-Dexmedetomidina na Sedação Pediátrica: Uma Meta-Análise.
Bibliographic record
Abstract
Esta meta-análise visa avaliar o tempo necessário para alcançar sedação efetiva em pacientes pediátricos utilizando a combinação de cetamina e dexmedetomidina (ketodex - KD), explorando seu potencial como alternativa segura e eficiente para manejo anestésico. O estudo busca oferecer evidências para melhorar a prática clínica em sedação pediátrica. Foram incluídos ensaios clínicos randomizados e estudos observacionais que investigaram o uso da KD em pacientes pediátricos. O desfecho primário analisado foi o tempo até a sedação efetiva, definido como o intervalo entre a administração do sedativo e o alcance de sedação adequada. Os dados foram extraídos por três revisores independentes, e o risco de viés foi avaliado utilizando as ferramentas RoB 2 e Newcastle-Ottawa. A análise estatística foi conduzida no software JASP, utilizando modelos de efeitos aleatórios para calcular as proporções e intervalos de confiança.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.022 | 0.010 |
| Meta-epidemiology (narrow) | 0.005 | 0.005 |
| Meta-epidemiology (broad) | 0.009 | 0.003 |
| Bibliometrics | 0.007 | 0.043 |
| Science and technology studies | 0.003 | 0.012 |
| Scholarly communication | 0.033 | 0.005 |
| Open science | 0.044 | 0.021 |
| Research integrity | 0.004 | 0.009 |
| Insufficient payload (model declined to judge) | 0.116 | 0.305 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; both teacher heads agree on what is shown here.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".