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Additional file 1 of Clinical outcomes in patients relapsed/refractory after ≥2 prior lines of therapy for follicular lymphoma: a systematic literature review and meta-analysis

2024· article· en· W6957971593 on OpenAlexaff

Bibliographic record

VenueFigshare · 2024
Typearticle
Languageen
FieldMedicine
TopicLymphoma Diagnosis and Treatment
Canadian institutionsGilead Sciences (Canada)
Fundersnot available
KeywordsTable (database)Meta-analysisSystematic reviewMEDLINESelection (genetic algorithm)Clinical trial

Abstract

fetched live from OpenAlex

Additional file 1: Table S1. Embase search strategy. Table S2. Cochrane Central Register of Controlled Trials search strategy. Table S3. MEDLINE search strategy. Table S4. Study selection criteria to identify trials for the systematic literature review. Table S5. Studies included in each meta-analysis. Table S6. Study quality assessment results. Table S7. Response criteria used for each study included in the meta-analysis. Table S8. Meta-analysis of response outcomes, separated by treatment category, a. Main analysis, b. With inclusion of off-label treatments. Table S9. Model selection across the Bayesian analyses. Table S10. Time-to-event meta-analysis results for supplemental models. Fig. S1. Meta-analysis of response outcomes, including off-label treatments, A) Overall response rate, B) Complete response. Fig. S2. Pooled KM curves for supplemental model including off-label treatments, A) PFS 3rd line plus, B) OS 3rd line plus, Fig. S3. Pooled KM curves for supplemental model including only SCT studies, A) PFS 3rd line plus, B) OS 3rd line plus.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.042
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.747
Threshold uncertainty score0.362

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.042
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0040.006
Bibliometrics0.0070.010
Science and technology studies0.0010.000
Scholarly communication0.0020.003
Open science0.0020.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.7470.030

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.055
GPT teacher head0.342
Teacher spread0.286 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designMeta-analysis
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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