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Record W6977223945 · doi:10.6084/m9.figshare.26640946

Additional file 4 of Long-term humoral and cellular immunity after primary SARS-CoV-2 infection: a 20-month longitudinal study

2024· article· en· W6977223945 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueFigshare · 2024
Typearticle
Languageen
FieldPhysics and Astronomy
TopicQuantum and Classical Electrodynamics
Canadian institutionsUniversity of TorontoUniversity Health NetworkToronto General Hospital
Fundersnot available
KeywordsCellular immunityHumoral immunityVaccinationImmune systemStatistical analysisLongitudinal studyWilcoxon signed-rank test

Abstract

fetched live from OpenAlex

Additional file 4: Supplementary Figure 4. Impact of SARS-CoV-2 vaccination on humoral and cellular immunity for S-small and non-S immunity. Analysis of a subset of 65 patients who received their first 2 vaccinations between two subsequent visits (Prior: A visit where the participant had not been vaccinated, Post: The subsequent visit, where the participant had received 2 vaccinations). (A) Percentage of SARS-CoV-2 spike (S)-specific CD4+ and CD8+ T cells analysed by AIM after stimulation with the S-small pool. (B) IFNγ production by SARS-CoV-2 S-specific cells (S-small pool). (C) SARS-CoV-2 nucleocapsid-specific IgG levels (D) Percentage of SARS-CoV-2 S-specific CD4+ and CD8+ memory T cells analysed by ICS after stimulation with the non-S peptide pool. (E) Percentage of SARS-CoV-2 non-S-specific CD4+ and CD8+ T cells analysed by AIM. (F) IFNγ production by SARS-CoV-2 non-S-specific cells. Horizontal line shows median Statistical comparisons were performed using Wilcoxon unpaired signed-ranks test adjusted using Bonferroni. *P ≤ 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Dataset · Consensus signal: none
Teacher disagreement score0.931
Threshold uncertainty score0.572

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.9310.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.260
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it