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Record W6980495113

Characterization of lBD and lBD Diagnostic Codes in the Elderly

2014· other· en· W6980495113 on OpenAlexaboutno aff

Bibliographic record

VenueMspace (University of Manitoba) · 2014
Typeother
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBiological Activity of Diterpenoids and Biflavonoids
Canadian institutionsnot available
Fundersnot available
KeywordsUlcerative colitisInflammatory bowel diseaseDiseaseDiagnosis codeElderly peopleMedical diagnosisHospital dischargeColitis
DOInot available

Abstract

fetched live from OpenAlex

Background: It is important to validate the use of inflammatory bowel disease (IBD) international classification of diseases (ICD) codes in the hospital discharge abstracts, specifically for the elderly as other colonic diseases (e.g. ischemic colitis) are more common in the elderly and could lead to miscoding. Methods: From the six hospitals in Winnipeg, elderly (>65 years) and young (<50 years) patients discharged with a diagnosis of IBD between April 1, 2007 and March 31, 2010 and a random selection of elderly patients with other colonic conditions were identified and their hospital charts reviewed. Results: 170 elderly and 85 young patients with IBD discharge diagnosis and 135 elderly with other gastrointestinal discharge diagnosis were included. For Crohn's disease (CD), single ICD codes had sensitivity of 98%, specificity 96% and a positive predictive value (PPV) of 94%; for ulcerative colitis (UC) 100%, 86% and 70% respectively. Ileocolonic disease was more common in younger CD patients (58.3%) while elderly patients were more likely to have ileal or colonic disease (p<0.05). The elderly IBD were more likely to be on 5-aminosalicylates prior to hospitalization (61% vs. 43%, p=0.041) while the young IBD were more likely to be prescribed biologics (21% vs. 6%, p=0.016) and immunomodulators (42% vs 21%, p=0.01 ). Conclusions: A single ICD-10 IBD code is satisfactory to identify elderly CD hospitalized patients, and although less accurate, still has good specificity to identify elderly UC patients. Biologicals and immunomodulators are used less often in the elderly IBD, even among those with disease severe enough to require hospitalization.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.830
Threshold uncertainty score0.975

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.184
Teacher spread0.176 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2014
Admission routes1
Has abstractyes

Explore more

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