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Record W6991123997

Evolutionary Persistence and Speciation under
\nAncient Asexuality

2023· dissertation· en· W6991123997 on OpenAlexaboutno aff

Bibliographic record

VenueKölner Universitäts PublikationsServer (Universität zu Köln) · 2023
Typedissertation
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicEvolution and Genetic Dynamics
Canadian institutionsnot available
Fundersnot available
KeywordsAsexualityGenetic algorithmPopulationAsexual reproductionEvolvabilityHuman evolutionary geneticsSexual reproductionEvolutionary ecologyPopulation genomicsExtinction (optical mineralogy)
DOInot available

Abstract

fetched live from OpenAlex

The enigma of why sexual reproduction persists in nature despite its many costs continues to challenge the field of evolutionary biology. Compared to sexual reproduction, asexuality is more straightforward. However, it is rare in animals and often regarded as an evolutionary dead-end. ‘Ancient asexuals’ challenge this view, as they successfully persisted over evolutionary time. Understanding how these evolutionary scandals thrive in the absence of sex will, in turn, provide insights into the selective advantage of sexual reproduction. 
\nThis thesis explored the consequences of ancient asexuality and emphasized its effects on genome evolution in natural populations. The oribatid mite Platynothrus peltifer was introduced as an ideal subject for studying ancient asexuality and speciation. Employing a comprehensive approach, I generated genome, transcriptome, and population data. Within this data, we found evidence of intra-individual haplotype divergence, conserved genomic synteny among populations, and notable inter-individual population variation. Thus, we proposed haplotypic independence to contribute to evolvability as a way to adapt and escape extinction in long-term asexuals. 
\nP. peltifer is known to exhibit multiple independent evolutionary lineages. Asexual speciation may be more prevalent in certain taxa, like oribatid mites, due to their distinctive ecological niches and long-term evolutionary persistence. Understanding how asexuals diversify into new species is crucial as it challenges traditional evolutionary paradigms, reveals hidden biodiversity, and provides insights into the dynamics of speciation, evolution, taxonomy, and conservation. Thus, this study delved into the complexities of species delimitation, while emphasizing the need for a holistic perspective in comprehending asexual speciation. I suggested speciation of the Japanese population and identified potential cryptic lineages in the Canadian population of P. peltifer. European populations lacked distinct phylogenetic boundaries and genetic differences. However, haplotypic divergence in European populations implied cohesion mechanisms on a global scale among geographical lineages. Furthermore, this work laid the foundation for future sex-asex comparisons in oribatid mites as it provided high-quality genomes of sexual and asexual oribatid mites. This will determine whether the observed effects are lineage-specific or general consequences of ancient asexuality.
\nThis study established a new protocol allowing for haplotype-specific genomics of tiny non-model-organisms. It discussed how ancient asexuals might have evolved and benefitted from their genome dynamics and how this facilitates asexual speciation. An in-depth analysis of Platynothrus peltifer provided evidence of its long-term asexuality and speciation. It introduced haplotypic independence as a way to allow for ‘evolution’ thus contributing to the persistence of ancient asexuals.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.754
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.229
Teacher spread0.214 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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