Characterization of a carbon source-dependent, phytohormone-responsive, free methionine-(R)-sulfoxide reductase from Komagataeibacter hansenii
Bibliographic record
Abstract
Komagataeibacter hansenii ATCC 23769 is a gram negative, non-pathogenic, acetic acid bacterium, best known for its ability to produce bacterial cellulose (BC). BC, an extracellular polysaccharide, is an important component of biofilms as it promotes anchoring to surfaces for nutrient acquisition and protection from environmental stress. BC has been long studied however, there is a lack of research pertaining to the regulation of BC production. In this thesis, the functional role of a putative free methionine sulfoxide reductase (MsrC) was characterized using a knockout mutant. The growth of the mutant was greatly affected by the presence of ethylene, abscisic acid and indole-3-acetic acid while oxidative stress increased BC production. Fructose-grown cultures produced more reactive oxygen species than in glucose. Oxidative stress upregulated genes involved with survival, growth, cellulose production, and stress defense. Therefore, MsrC is both phytohormone and oxidative stress responsive, coordinating cellular functions such as growth and BC production.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".