LONGTERM RISK OF DYSGLYCEMIA AFTER SYMPTOMATIC GASTROENTERITIS DUE TO BACTERIAL WATER CONTAMINATION: THE WALKERTON HEALTH STUDY
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
In May 2000, the Walkerton Ontario municipal water supply was contaminated with Escherichia coli O157:H7 and Campylobacter, causing widespread gastroenteritis and hemolytic uremic syndrome (HUS). Previous studies indicate HUS may be complicated by insulin deficiency. We performed a retrospective cohort study with prospective follow-up to examine whether individuals who developed gastroenteritis without overt HUS during the outbreak are at increased risk of diabetes mellitus, impaired fasting glucose or impaired glucose tolerance. From 2002-2005, 3259 residents of Walkerton and surrounding areas who were >10 years old with no known history of diabetes or impaired fasting glucose completed annual questionnaires and fasting plasma glucose and oral glucose tolerance tests. Participants were categorized regarding presence of gastroenteritis during the outbreak using data from multiple sources. After a mean follow-up of 4.5+1.0 years, there were no significant differences between groups in age- and sex-standardized rates of the primary composite outcome (asymptomatic: 11.0% [95% CI 8.8-13.2%]; possible gastroenteritis: 11.6% [95% CI 9.0-14.4%]; confirmed gastroenteritis: 10.9% [95% CI 9.4-12.5%]; (trend p=0.944). Gastroenteritis without HUS does not result in an increased risk of abnormal glucose homeostasis up to 5 years after the initial infection.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it