AComparison of the Effects of Anesthesia with Ketamin-Sevoflurane and Ketamin-Propofol on Cardiorespiratory Variables in Patients Undergoing Diagnostic Cardiac Angiography at Children’s Medical Center in 2014
Bibliographic record
Abstract
"Pediatric patients undergoing cardiac catheterization need general anesthesia with the least alteration in hemodynamic status. The aim of this study was to compare the effects of ketamine-propofol and ketamine-sevoflurane on hemodynamic changes in pediatric patients undergoing cardiac catheterization.In this randomized double-blinded clinical trial, sixty 2-8 year-old patients met the inclusion criteria and were randomly divided into two equal groups (n=30): the KS group (1 mg/kg intravenous ketamine and 2.5 minimum alveolar concentration (MAC) volatile sevoflurane for induction followed by 1.5 MAC sevoflurane which was reduced to 1 MAC after 10 min) and the KP group (0.1 ml/kg of premixed solution of 80 mg/ml ketamine and propofol for induction followed by a maintenance solution of 0.01 mg/kg min). Heart rate (HR), blood pressure, and arterial oxygen saturation were recorded and compared prior to and after the induction of anesthesia, prior to and after catheter insertion, and together with the measurement of systemic and pulmonary atrial blood pressure during angiography. Pain was recorded using Children’s Hospital of Eastern Ontario Pain Scale (CHEOPS) immediately after surgery and every 10 min until recovery and discharge.None of the patients had significant changes in blood pressure and heart rate. There was no significant difference in cardiopulmonary assessment using angiography. The mean of CHEOPS in the KS group was significantly lower than that in the KP group 40 and 50 min after surgery. There was no significant difference between the groups in terms of mean CHEOPS trend. Patients in the KS group recovered and were discharged from the recovery room faster than patients in the KP group.Based on our result, the ketamine-sevoflurane combination has no significant advantages over ketamine-propofol combination. However, its shorter recovery time has made it the preferred method of general anesthesia."
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".