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Record W7026820338

Bacteriophages, a Solution to the Destruction of Antibiotic-Resistant Bacteria

2024· article· en· W7026820338 on OpenAlexaboutno aff

Bibliographic record

VenueDOAJ (DOAJ: Directory of Open Access Journals) · 2024
Typearticle
Languageen
FieldChemistry
TopicAnalytical chemistry methods development
Canadian institutionsnot available
Fundersnot available
KeywordsBacteriaBacteriophagePhage therapyVirusAntibiotic resistance
DOInot available

Abstract

fetched live from OpenAlex

Bacteriophage is the generic name given to microorganisms that can destroy bacteria. The name (which comes from the Latin bacteria and the Greek φᾰγεῖν phagein - "to eat", "to devour") was introduced by the Canadian bacteriologist Félix d'Herelle in 1917, the year he discovered a virus possessing such characteristics. Also called bacteria-eating viruses, bacteriophages represent a group of viruses with a destructive effect on bacteria (lytic effect), being widespread in nature, in all living environments (water, soil, air). Discovered during the First World War and developed in the 1920s and 1930s, phage therapy is currently making a comeback and enjoying a renewed interest in countries such as the USA, Belgium and France, in parallel with the development of antibiotic resistance, in the face of the increasing resistance of bacteria to antibiotics, a challenge for the whole planet. Today, phage therapy has begun to be used to disinfect food. Also, before surgery, in some hospitals, bacteriophages are sprayed in the operating rooms to reduce the risk of infection. Through their mechanism of action, bacteriophages can become a kind of additional immune system for organisms, and phage therapy, a therapy to be studied and perspective for maintaining human and animal health.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.003
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.001
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0030.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.188
GPT teacher head0.518
Teacher spread0.330 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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