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Record W7027434726

Comparing the Efficacy of Intralesional Verapamil Hydrochloride vs Triamcinolone Acetonide in Treatment of Keloids/ Hypertrophic Scars

2022· article· en· W7027434726 on OpenAlexaboutno aff

Bibliographic record

VenueDOAJ (DOAJ: Directory of Open Access Journals) · 2022
Typearticle
Languageen
FieldMedicine
TopicDermatologic Treatments and Research
Canadian institutionsnot available
Fundersnot available
KeywordsTriamcinolone acetonideVerapamilKeloidGroup BRandomized controlled trialHypertrophic scar
DOInot available

Abstract

fetched live from OpenAlex

Objective: To compare the mean VSS score of intra lesional Verapamil Hydrochloride vs Triamcinolone Acetonide in treatment of keloids/ hypertrophic scars. Study type, settings & duration: This non randomized controlled trial was conducted in Sheikh Zayed Hospital, Rahim Yar Khan from July 2019 to June 2020. Methodology: In this study the cases of either gender and age more than 12 years were included irrespective of duration of keloid via non probability consecutive sampling. A total of 100 cases were included. The cases were divided into two equal groups by lottery method. The cases in group A were treated with intralesional Triamcinolone (40mg/ml) while group B was treated with intralesional Verapamil (2.5mg/ml).In both groups, session was repeated every 3 weeks for a maximum of 8 sessions or until complete flattening of the scar. Patients were accessed on the basis of Vancouver scar scale (VSS). VSS score was compared between both groups pre and post treatment. Results: The mean age in group A and B was 22.16±9.01 vs. 22.68±8.93 years respectively (p =0.49). The mean duration of keloid or scar was 6.58±1.54 months in group A and 6.46±1.42 in group B with p =0.31.VSS score after treatment was 2.41±1.19 vs 1.65±0.93 with respect to change in Pliability score and it was 1.61±0.81 vs 1.25±0.72 in terms of height in Verapamil vs Triamcinolone group with p values of 0.05 and 0.04 respectively. Conclusion: There is statistically significant difference in Triamcinolone group with respect to change in Pliability score and height as compared to......

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0010.000
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.334
GPT teacher head0.548
Teacher spread0.213 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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