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Record W7038854256

Investigation of viral infections of ring-billed gulls (Larus delawarensis) in southern Ontario, Canada

2002· dissertation· en· W7038854256 on OpenAlexaboutno aff

Bibliographic record

VenueThe Atrium (University of Guelph) · 2002
Typedissertation
Languageen
FieldMedicine
TopicInfluenza Virus Research Studies
Canadian institutionsnot available
Fundersnot available
KeywordsNewcastle diseaseVirusSerologyAntibodyInfluenza A virus subtype H5N1Viral sheddingVirulenceCircovirus
DOInot available

Abstract

fetched live from OpenAlex

Between mid-May and mid-July 2000, 360 ring-billed gulls ('Larus delawarensis') were sampled (120 adults; 120 three weeks old; 120 five weeks old). The prevalence of antibodies specific to avian influenza virus (AIV) H13 differed significantly among age groups (92%, 53%, and 15% for adult, five-, and three-week-old gulls, respectively). Hemagglutinating agents, all of which were avian influenza A virus H13N6, were isolated from the cloacal swabs/tissue samples of 53 gull chicks. Three-week old chicks were 3.24 times more likely to be shedding AIV than five-week-old chicks. Infection with Newcastle disease virus (NDV), previously rare in gulls on the lower Great Lakes, was common (90%) based on the serologic findings; its clinical significance is unknown. The prevalence in adults was significantly lower (79%) than in three-week-old gulls (98%) or five-week-old gulls (93%). Newcastle disease virus was not isolated from any of the gulls. The H13N6 avian influenza A subtype has low virulence in gulls. However, lesions such as lymphocytic infiltration in heart, kidney, pancreas, liver, and respiratory tract were significantly associated with the presence of antibodies against AIV and not with the presence of antibodies against NDV or isolation of AIV from cloacal, kidney, or lung tissues. Chickens are susceptible to infection with an AIV H13N6 after intravenous inoculation. No clinical signs were seen but the virus replicated in renal tubular epithelial cells and was associated with lymphocytic interstitial nephritis. These results are similar to other low pathogenic AIV isolated from waterfowl. Circovirus infection was only detected in 6% of the juvenile birds. Inclusions were restricted to the lymphoreticular tissue. No significant differences between infected and non-infected birds were seen in eight different biological paramenters. The first evidence of circovirus infection, in a retrospective study, was in a juvenile ring-billed gull in 1973. Cirvovirus-like inclusions also were seen in juvenile herring gulls ('Larus argentatus') and a great black-backed gull ('Larus marinus'). Birds with circovirus-like inclusions were 2.89 times (odds ratio) more likely to have septicemia/aspergillosis than birds with no circovirus-like inclusions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.142
Threshold uncertainty score0.287

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.254
Teacher spread0.220 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2002
Admission routes1
Has abstractyes

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