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Record W7039483221

Long-term effects of concussion: Investigating the relationship between sensory gating and motor learning

2023· dissertation· en· W7039483221 on OpenAlexaff

Bibliographic record

VenueUWSpace (University of Waterloo) · 2023
Typedissertation
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicTraditional and Medicinal Uses of Annonaceae
Canadian institutionsUniversity of Waterloo
Fundersnot available
KeywordsSensory gatingGatingSomatosensory systemSensory systemFacilitationProprioceptionMotor learningSession (web analytics)Task (project management)
DOInot available

Abstract

fetched live from OpenAlex

Motor learning relies on the sensorimotor system to interpret, adapt, and integrate sensory inputs to guide motor behavior. A key tenet of the somatosensory system is the ability to inhibit irrelevant information from the CNS to protect higher cortical areas from information overload (sensory gating). Movement and attention can contribute to this process through movement-related gating and relevancy-based facilitation, respectively. Sensory gating occurs at early cortical processing stages and has been shown to be impacted in individuals with a history of concussion. Past work from our lab found a delay in relevancy-based facilitation in a group with a history of concussion compared to healthy controls. The current work aimed to understand the behavioral manifestations that result from disruptions to relevancy-based gating modulations at early cortical processing stages in the concussion population. A total of 40 participants were recruited to participate in this study with 25 in the concussion history group (Hx) and 15 in the control group (No-Hx). This study consisted of 2 experimental sessions that occurred 24 hours apart. During session 1, somatosensory-evoked potentials (SEPs) were elicited via median nerve stimulation while subjects performed a task that manipulated their focus of attention toward or away from proprioceptive feedback. Subjects then completed an implicit motor sequence learning task relying solely on proprioceptive cues. Individuals performed a retention test at session 2, followed by a visual attentional blink (AB) task. The AB is a phenomenon elicited by the rapid presentation of sequential targets which results in reduced accuracy of detecting the second target at the expense of detecting the first target. The No-Hx performed the implicit learning task at session 1 and a retention test at session 2 because SEP and AB data were compared to control data previously collected by this lab. SEP data replicated past work showing an absence of relevancy-based facilitation at early cortical processing stages (N20-P27) that emerged at later processing stages. Our Hx showed evidence of relevancy-based facilitation at either the P50-N70 or the N70-P100 consistent with past work that found this to occur at the N70-P100. Performance on the learning task was not significantly different between the Hx and No-Hx. Performance on the AB task revealed greater AB magnitude in the Hx compared to the No-Hx. Collectively, these results suggest a compensatory strategy in the Hx that enables them to learn to the same degree as controls. However, when the attentional system is taxed with high temporal demands there are decrements in performance. These results are of particular importance given that these individuals are at an increased risk of sustaining subsequent concussions, and musculoskeletal injuries.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.350
Threshold uncertainty score0.469

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.236
Teacher spread0.216 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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