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Record W7043399506

Statistical power of epidemiological studies of low dose levels of ionizing radiation and cancer

2020· dissertation· en· W7043399506 on OpenAlexaboutno aff

Bibliographic record

VenueUniversity Library (University of Saskatchewan) · 2020
Typedissertation
Languageen
FieldMedicine
TopicRadiation Dose and Imaging
Canadian institutionsnot available
Fundersnot available
KeywordsIonizing radiationEpidemiologyCancerIncidence (geometry)Statistical powerCancer incidenceCancer registry
DOInot available

Abstract

fetched live from OpenAlex

The purpose of this research is to inspect the statistical power of studies that investigate\nthe effects of low dose ionizing radiation on the incidence of/mortality from cancer. I use\na procedure proposed in a similar study to handle a problem regarding the incidence of\nchildhood leukemia from background ionizing radiation. I study this procedure critically\nand make some adjustments to make its performance better. I also propose some substitute\nmethods to the methods proposed in the aforementioned reference in order to calculate\nthe power. In addition, I propose other methods not used in the study mentioned above.\nI evaluate the efficiency of my proposed approaches using simulated data. The improved\nmethod can be applied to the National Dose Registry of Canada (NDR) to produce the\npower curves. The outcomes then can be used to propose the most suitable study design.\nSome of the previous epidemiological studies based on NDR can also be evaluated in terms\nof power.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.225
metaresearch head score (Gemma)0.514
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (broad)
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.998
Threshold uncertainty score0.956

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2250.514
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.004
Bibliometrics0.0060.005
Science and technology studies0.0010.006
Scholarly communication0.0040.004
Open science0.0020.003
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0060.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.261
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designSimulation or modeling
DomainMethods
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes1
Has abstractyes

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