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Record W7044079556

Understanding changes in peripheral and central excitability following submaximal
\ncontractions

2016· dissertation· en· W7044079556 on OpenAlexaff

Bibliographic record

VenueMemorial University Research Repository (Memorial University) · 2016
Typedissertation
Languageen
FieldNeuroscience
TopicTranscranial Magnetic Stimulation Studies
Canadian institutionsMemorial University of Newfoundland
Fundersnot available
KeywordsHyporeflexiaLafora diseaseMagnetic resonance neurographyTachyphylaxisFusible alloyLimiting
DOInot available

Abstract

fetched live from OpenAlex

The objective of this thesis was to examine the effects of brief (2s), non-fatiguing, \nsubmaximal (50% of MVC) and intermittent (2s on, 2s off) contractions on measures of central \nand peripheral excitability. Nine resistance-trained males completed a contraction protocol \nconsisting of 5 such contractions of the elbow flexors. Pre-, immediately post-, and 5 minutes \npost-contractions the participants received transcranial magnetic stimulation (TMS), \ntransmastoid electrical stimulation (TMES), peripheral nerve stimulation, and motor point \nstimulation to elicit motor-evoked potentials (MEPs), cervicomedullary-evoked potentials \n(CMEPs), maximal muscle compound action potentials (Mmax), and peak twitch force (PT), \nrespectively. All MEPs and CMEPs were normalized to Mmax. In addition, correlations between \ncentral and peripheral excitability were analyzed in order to determine if the two are separate \nentities or related. Finally, all measurements were taken both at rest, as well as during a slight \n(5% of MVC) contraction. This allowed us to determine if the changes in central and peripheral \nexcitability, as well as the correlations between the two, were state-dependent. Results showed \nan increase in corticospinal excitability (CSE) that was state-dependent, a decrease in spinal \nexcitability that was not state-dependent, and an increase in muscle excitability that was not \nstate-dependent following the contraction protocol. There was a positive correlation between \nCSE and peripheral excitability that was state-dependent, and a negative correlation between \nspinal excitability and peripheral excitability that was not state-dependent. Since some of the \ntrends observed were state-dependent, the major finding of this thesis is that results obtained at \nrest should not be generalized to movement situations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.092
GPT teacher head0.297
Teacher spread0.205 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2016
Admission routes1
Has abstractyes

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