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Record W7047659284

Gruppe B-streptokokker i svangerskapet

2009· dissertation· en· W7047659284 on OpenAlexaboutno aff

Bibliographic record

VenueDuo Research Archive (University of Oslo) · 2009
Typedissertation
Languageen
FieldEngineering
TopicPhotocathodes and Microchannel Plates
Canadian institutionsnot available
Fundersnot available
KeywordsPregnancyRandomized controlled trialAntibioticsDeveloped countryArgument (complex analysis)Risk factorAntibiotic prophylaxisAntibiotic therapy
DOInot available

Abstract

fetched live from OpenAlex

Abstract\n\nThe Group B Streptococcus is still the leading cause of infections in newborns. There is effective treatment available, but no global consensus exists on how to reach those women who will benefit from intrapartum antibiotic prophylaxis. As a result, several countries have developed national guidelines on how to prevent GBS-disease. USA, Canada and many countries in Europe(Spain, Belgium, Italy) have chosen a universal screening strategy. This means screening of every pregnant woman in gestational week 35-37 and antibiotic treatment of those with GBS colonization. This strategy differs from the one used in Norway as well as in the UK, where the approach is to treat pregnant women based on risk factors associated with GBS-disease, without any screening. \nIn this paper we discuss the different views, without making any conclusions which alternative is best. \nIn order to look into the different arguments, we review several articles with different screening-strategies.\nIn our material the main argument for pregnancy screening is the clear observed reduction of morbidity and mortality associated with GBS-disease. However, this approach will lead to excessive use of antibiotics, and the subsequent risk of serious antibiotic anaphylaxis and development of antibiotic resistance. \nAt present there is lack of good randomized controlled trials where screening- versus risk based strategies are compared. Therefore no valid conclusions can be made from an evidence based view. However, before development and introduction of a vaccine, there may never be one universal strategy that every country will benefit from.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.483
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.258
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2009
Admission routes1
Has abstractyes

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