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Record W7047659284

Gruppe B-streptokokker i svangerskapet

2009· dissertation· en· W7047659284 on OpenAlexaboutno aff

Bibliographic record

VenueDuo Research Archive (University of Oslo) · 2009
Typedissertation
Languageen
FieldEngineering
TopicPhotocathodes and Microchannel Plates
Canadian institutionsnot available
Fundersnot available
KeywordsPregnancyRandomized controlled trialAntibioticsDeveloped countryArgument (complex analysis)Risk factorAntibiotic prophylaxisAntibiotic therapy
DOInot available

Abstract

fetched live from OpenAlex

Abstract\n\nThe Group B Streptococcus is still the leading cause of infections in newborns. There is effective treatment available, but no global consensus exists on how to reach those women who will benefit from intrapartum antibiotic prophylaxis. As a result, several countries have developed national guidelines on how to prevent GBS-disease. USA, Canada and many countries in Europe(Spain, Belgium, Italy) have chosen a universal screening strategy. This means screening of every pregnant woman in gestational week 35-37 and antibiotic treatment of those with GBS colonization. This strategy differs from the one used in Norway as well as in the UK, where the approach is to treat pregnant women based on risk factors associated with GBS-disease, without any screening. \nIn this paper we discuss the different views, without making any conclusions which alternative is best. \nIn order to look into the different arguments, we review several articles with different screening-strategies.\nIn our material the main argument for pregnancy screening is the clear observed reduction of morbidity and mortality associated with GBS-disease. However, this approach will lead to excessive use of antibiotics, and the subsequent risk of serious antibiotic anaphylaxis and development of antibiotic resistance. \nAt present there is lack of good randomized controlled trials where screening- versus risk based strategies are compared. Therefore no valid conclusions can be made from an evidence based view. However, before development and introduction of a vaccine, there may never be one universal strategy that every country will benefit from.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.023
Threshold uncertainty score0.078

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0000.001
Scholarly communication0.0020.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0230.006

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.258
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2009
Admission routes1
Has abstractyes

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