Sacrifice or Salvation: How can Animal Lives be Spared and Human Health Improved by Toxics Reform?
Bibliographic record
Abstract
This dissertation investigates the complexities of the entwined relations between animal cognition, the use of animals in toxicity testing, and the proliferation and impacts of harmful chemicals in our society. It asks how, in light of the most current research on animal sentience and the ethics of responsibility, a reorientation of chemical testing at a theoretical, ethical and practical level could spare animal suffering and improve human health outcomes. Its starting point is the unfolding scientific research on animal cognition, and the consequent implications for reconsidering the ethical relationships, historically established and currently assumed, between human and non-human animals. The central issue, which infuses this dissertation, is whether humans are obliged by this knowledge to expand our moral arena to encompass animals, to acknowledge their entitlement not to be used for toxicity experimentation, and the implications of such an entitlement for the future use of animals in toxicity testing. \nThe work is based on a social constructivist process centred on the multiple facets of toxicity testing – the philosophical viewpoints of those who have expressed concern for the well-being of animals, governments’ animal protection laws that fail to spare animals from painful experimentation, toxics laws that promote the use of animals in toxicity tests, the pain and suffering of the tests themselves, the championing of the mouse as the favoured animal for experimentation, and the limitations and failure of toxicity testing itself to safeguard public health and the environment from widespread contamination. In addition, this examination of toxicity testing looks at the potential differences between advocates of expanded testing of toxic chemicals and animal advocates concerned about the implications of expanded testing for the increased use of animals. Finally, building on qualitative methods for assessing the current state of knowledge regarding the use of animals in toxicity testing, this dissertation evaluates how this system could be redrawn to both spare animals and better gauge the toxicity of chemicals.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.017 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".