Characterization of Clostridium difficile from patients in Ontario hospitals
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
The characteristics of 'Clostridium diffiile' strains recovered from patients in Ontario healthcare facilities were studied. ' Clostridium difficile' toxin ELISA positive fecal samples were collected from 21 Ontario healthcare facilities between March 2005 and April 2006. Positive isolates were obtained from 1080/1152 (94%) samples, and were PCR-ribotyped. Presence of 'C. difficile' toxins A, B and CDT ribotypes was determined. Antimicrobial susceptibility was tested with the antimicrobials metronidazole, vancomycin, levofloxacin and clindamycin using E-tests. Presence of 'tcdC' gene deletion and toxinotyping was performed on all 39 distinct ribotypes. One ribotype accounted for 25% of isolates, while ribotype 027/NAP1, an internationally recognized outbreak strain, accounted for 19% of isolates. CDT prevalence was unexpectedly high (34.8%), and 6 ribotypes had a deletion in the 'tcdC' gene. One isolate showed reproducible metronidazole resistance but resistance was eventually lost during serial passage culture. 1080, 1076 and 0 isolates were susceptible to vancomycin, clindamycin and levofloxacin respectively.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it