Examining the Role of Biopsychosocial Factors in Disability Among Individuals with Inflammatory Bowel Disease
Bibliographic record
Abstract
IBD is an inflammatory disease that affects the gastrointestinal tract, encompassing two conditions (Crohn’s disease and ulcerative colitis). IBD negatively affects patients in a physical and psychosocial manner, which significantly impacts their quality of life. Related to quality of life is disability, which is an under-researched topic in the IBD literature. Models theorize that disability is the result of a disease and its related impairments, limitations, and restrictions it causes to an individual and their life. Environmental and psychosocial factors are also theorized to affect this process of disablement. Biopsychosocial factors such pain, depression, pain catastrophizing, and social support have all been linked to IBD disability-related outcomes, but no multivariate research has examined all of these factors simultaneously. This study aimed to elucidate the role of psychosocial factors in the process of disablement in an outpatient tertiary care IBD sample. Depressive symptoms, pain catastrophizing, and perceived social support were examined as mediators in the relationship between pain and pain-related disability cross-sectionally and longitudinally. Alternate models exploring feedback effects amongst disability and pain, and potential moderators (gender, disease type) of the mediation relationships were also tested. Cross-sectionally, depressive symptoms and pain catastrophizing, but not perceived social support, were significant mediators in the relationship between pain and pain-related disability. Support was found for feedback effects, such that disability predicted pain both cross-sectionally (through depressive symptoms as a mediator) and longitudinally (directly). These findings augment the research supporting a biopsychosocial model of IBD disability. Further, these results highlight the importance of targeting psychological factors such as depressive symptoms and pain catastrophizing in the treatment of individuals with IBD.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.006 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.002 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".