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Record W7065693439

Electroencephalographic, physiologic, and behavioural evaluation of cervical dislocation methods for on-farm euthanasia of poultry

2019· dissertation· en· W7065693439 on OpenAlexfundno aff

Bibliographic record

VenueThe Atrium (University of Guelph) · 2019
Typedissertation
Languageen
FieldVeterinary
TopicAnimal testing and alternatives
Canadian institutionsnot available
FundersNatural Sciences and Engineering Research Council of CanadaConsejo Nacional de Ciencia y TecnologíaOntario Ministry of Agriculture, Food and Rural AffairsChicken Farmers of SaskatchewanPoultry Industry Council
KeywordsElectroencephalographyBarbiturateIsoelectric focusingPentobarbitalElectrophysiology
DOInot available

Abstract

fetched live from OpenAlex

Poultry euthanasia is a routine procedure with several welfare issues and on-farm limitations. Cervical dislocation is conditionally acceptable euthanasia method due to prolonged time to loss of sensibility and death; while barbiturate overdose is considered the gold standard method across species but is limited in practical use on-farm because barbiturates are controlled drugs. The main goal of this research was to evaluate manual cervical dislocation (CD) and mechanical cervical dislocation (MCD, using a novel device) in two different age groups of turkeys and two strains of chicken using electroencephalography (EEG) and physiologic and behavioural analysis, and compare them to barbiturate overdose. Method efficacy was assessed using spectral analysis measures and latency to isoelectric EEG (electrocerebral inactivity). Finally, EEG changes were compared to commonly used behavioural and physiologic responses as indicators of death. A minimal anesthesia model (1.5% isoflurane/O2) was used and anesthesia was discontinued immediately prior to euthanasia application to minimize welfare concerns related to physical method use. Intravenous pentobarbital sodium (1 mL/4.5 kg) induced immediate brain death in all birds with EEG activity significantly decreased at 15s post injection and corresponding isoelectric EEG in all recordings, regardless of age, strain or species. In turkeys, EEG activity during the 300s evaluation period showed changes related to brain death at 120-135s after CD and 300s after MCD application. Isoelectric EEG patterns were consistently observed after CD but not after MCD. Similarly, in end-of-lay hens, time to brain death was observed either at 135s and 285s following CD and MCD application, respectively. Again, isoelectric EEG patterns were particularly inconsistent after MCD application. The association between EEG changes and behavioural and physiologic responses was inconsistent between methods. These studies demonstrate that the MCD device used is not suitable for euthanasia of mature and young turkeys or end-of-lay hens due to prolonged time to brain death. CD was a more effective euthanasia method than MCD but showed a prolonged time to brain death. In contrast, intravenous barbiturate overdose is the preferred method of euthanasia for poultry but has practical limitations. Our findings provide quantitative information for recommendations concerning on-farm euthanasia of poultry.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.965
Threshold uncertainty score0.558

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.178
GPT teacher head0.415
Teacher spread0.237 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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