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Record W7066041982

Evaluation des technologies de santé au niveau international (impact sur le développement des médicaments)

2011· other· fr· W7066041982 on OpenAlexaboutno aff

Bibliographic record

VenueOpenGrey (Institut de l'Information Scientifique et Technique) · 2011
Typeother
Languagefr
FieldPhysics and Astronomy
TopicX-ray Spectroscopy and Fluorescence Analysis
Canadian institutionsnot available
Fundersnot available
KeywordsContext (archaeology)LimitingOrder (exchange)
DOInot available

Abstract

fetched live from OpenAlex

Pendant longtemps, l'évaluation de la valeur d un médicament et de sa place dans la stratégie de prise en charge d'une pathologie en vue d un remboursement était nettement distincte de l'évaluation scientifique et secondaire à cette dernière. Cette deuxième évaluation était couramment évoquée comme étant le 4ème obstacle à la mise sur le marché d un médicament, après les trois évaluations indispensables de la qualité, de l'efficacité et de la sécurité. Cependant les évaluations de valeur relative, qu elles soient d efficacité ou de coût, deviennent de plus en plus intriquées dans le processus d enregistrement et de commercialisation. Après une présentation générale de l Evaluation des Technologies de Santé, nous décrivons son utilisation dans les processus décisionnels des autorités de santé du monde en nous focalisant plus particulièrement sur le Royaume-Uni, la France, l Allemagne, l Australie, le Canada et les Etats-Unis. Puis nous discuterons les limites de l utilisation de l Evaluation des Technologies de Santé et de ses conséquences pour les compagnies pharmaceutiques souhaitant enregistrer et commercialiser leurs produits dans ces pays.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Scholarly communication, Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.881
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0060.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.004
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0080.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.315
Teacher spread0.279 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designOther design
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2011
Admission routes1
Has abstractyes

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