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Record W7097050311

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2016· article· en· W7097050311 on OpenAlexaboutno aff

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicFungal and yeast genetics research
Canadian institutionsnot available
Fundersnot available
KeywordsASK1Mitogen-activated protein kinase kinaseMAP2K7MAP kinase kinase kinaseCyclin-dependent kinase 2Cyclin-dependent kinase 9Protein kinase Ac-Raf
DOInot available

Abstract

fetched live from OpenAlex

d i [1-5]. In yeast, the serine/threonine protein kinase Ste20 regulates a mitogen- activated protein kinase pathway death, cytoskeletal reorganization, growth, and differenti-ation [9-15]. A novel Ste20-related kinase was previously Storbeck et al. Skeletal Muscle 2013, 3:16 http://www.skeletalmusclejournal.com/content/3/1/16a role for SLK in cell death, it is also expressed at high2Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canadaconsisting of the Ste11 protein kinase (a mitogen-activated protein kinase kinase; MEKK), Ste7 protein kinase (a mitogen-activated protein kinase kinase; MEK), and Fus3/ Kss1 protein kinase (a mitogen-activated protein kinase; MAPK) involved in the control of mating response [6]. identified [16] and termed Ste20-like serine/threonine pro-tein kinase (SLK) [17-19]. Overexpression of SLK has been shown to induce breakdown of actin stress fibers and cell death in various systems [19-22]. A role for SLK in cell mi-gration and cell-cycle progression has also been shown [23-30]. During murine embryogenesis, SLK is preferentially expressed in muscle and neuronal lineages [31]. Despite

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.779
Threshold uncertainty score0.000

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.001
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0010.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.2210.140

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.260
Teacher spread0.250 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2016
Admission routes1
Has abstractyes

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