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Record W7098764505

CMAJ OPEN

2016· article· en· W7098764505 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldChemistry
TopicPlant-Derived Bioactive Compounds
Canadian institutionsnot available
Fundersnot available
KeywordsLiver transplantationHepatitis C virusAsymptomaticLiver diseaseHepatocellular carcinomaPopulationHepatitis CDiseaseChronic liver disease
DOInot available

Abstract

fetched live from OpenAlex

Chronic hepatitis C virus (HCV) infection is a leading cause of cirrhosis, hepatocellular carcinoma and liver transplantation in Canada.1 These complications are expected to increase substantially over the next decade2,3 and cause more years of life lost owing to mortality and subopti-mal health compared with any other infectious disease.4 Canadian guidelines advocate testing for HCV in people with evidence of liver disease or risk factors including injec-tion drug use, receipt of blood products before 1992, and those from endemic countries.5 However, several character-istics of HCV suggest that more widespread screening may be beneficial. First, HCV infection is common. Although the exact prevalence is unknown, at least 250 000 Canadians (0.8 % of the population) are likely infected.2,3 Second, most patients are asymptomatic until advanced liver disease has developed; thus, many patients with HCV are unaware of their HCV infection (21%–70 % in Canada3,6 and 50%–75% in the United States).7 Third, therapies are available that cure the infection in over 80 % of patients,8,9 arrest progres-sion of liver disease and reduce mortality.10 Based on these characteristics, recent US guidelines advocated one-time screening for HCV antibodies in individuals born between Acceptability and yield of birth-cohort screening for hepatitis C virus in a Canadian population being screened for colorectal cancer: a cross-sectional study

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.751
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0150.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.270
Teacher spread0.237 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Quick stats

Citations0
Published2016
Admission routes1
Has abstractyes

Explore more

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