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Record W7098838425

(6):611-5. DOI:10.1503/cmaj.1050077 Guidelines for STEMI

2016· article· en· W7098838425 on OpenAlexaboutno aff

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicBerberine and alkaloids research
Canadian institutionsnot available
Fundersnot available
KeywordsConventional PCIThrombolysisMyocardial infarctionPercutaneous coronary interventionIntervention (counseling)
DOInot available

Abstract

fetched live from OpenAlex

adaptation of the ST-elevation myo-cardial infarction (STEMI) guidelines. They have appropriately emphasized the importance of time to reperfusion, whether thrombolysis or primary per-cutaneous coronary intervention (PCI) is used. Although primary PCI may be superior to thrombolysis when per-formed in a timely manner, this ben-efit may be attenuated or lost alto-gether when PCI is delayed more than 60 minutes.2 However, it may be possi-ble to derive the benefits of primary PCI without the inherent treatment delay by administering thrombolysis followed by immediate transfer for PCI. This strategy, termed “facilitated PCI, ” may be the optimal mode of reperfusion for many patients in Canada, where interventional centres are regionalized. Although early stud-ies failed to show a benefit of routine PCI immediately after thrombolysis,3 PCI technology has changed consider-ably in recent years. More recent stud-ies have indicated that facilitated PCI may indeed be safe and effective,4 but larger studies are needed to provide definitive answers. The TRANSFER-AMI trial, initi-ated by Canadian investigators and funded by the Canadian Institutes of Health Research, will randomly assign approximately 1200 high-risk STEMI patients treated with thrombolysis in non-PCI hospitals to be transferred im-mediately for facilitated PCI or to re-ceive standard care. This study could have a significant impact on the treat-ment of STEMI in Canada, and we strongly encourage Canadian centres to participate (for further information, see

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.454
Threshold uncertainty score0.778

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0030.004
Insufficient payload (model declined to judge)0.4540.301

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.201
GPT teacher head0.449
Teacher spread0.248 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2016
Admission routes1
Has abstractyes

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Same topicBerberine and alkaloids researchFrench-language works237,207