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Record W7101857376 · doi:10.5281/zenodo.17447866

What are the costs, benefits, and harms of biomedical data reuse and of not reusing the data?

2025· article· W7101857376 on OpenAlexaboutno aff

Bibliographic record

VenueZenodo (CERN European Organization for Nuclear Research) · 2025
Typearticle
Language
FieldComputer Science
TopicResearch Data Management Practices
Canadian institutionsnot available
FundersEuropean Commission
KeywordsReuseStakeholderCorporate governanceData governanceHealth dataValue (mathematics)Presentation (obstetrics)Data collection

Abstract

fetched live from OpenAlex

This presentation reports on a scoping review of how the costs, benefits, harms, and cost savings associated with the reuse and non-reuse of biomedical data and samples are measured across health systems, research contexts, and populations. We report on how these outcomes have been quantified for different data types, stakeholder groups, populations, and areas of biomedical research using bibliometric, qualitative, and simulation approaches. We discuss gaps in the measurement of benefits, harms, costs and cost savings. We discuss how these measures and the impact of biomedical data reuse depends on the stakeholder group, context, data type, and governance conditions. We situate the discussion within broader questions of trust, transparency, and value creation in health data ecosystems, referencing case studies from Europe and Canada as well as insights from initiatives such as e-Estonia. Using a systems thinking lens, we argue that provenance metadata, living metrics, and stakeholder-specific value indicators are essential to achieving responsible, equitable data reuse.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.238
metaresearch head score (Gemma)0.531
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Open science
Consensus categoriesMetaresearch
DomainCandidate signal: Reproducibility · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.996
Threshold uncertainty score0.940

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2380.531
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.005
Bibliometrics0.0150.019
Science and technology studies0.0030.017
Scholarly communication0.0160.029
Open science0.0040.010
Research integrity0.0050.005
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.190
GPT teacher head0.345
Teacher spread0.154 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designTheoretical or conceptual
DomainReproducibility
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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