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S3047 Surgical vs Conservative Management of Patients With Adhesive Small Bowel Obstruction: An Updated Systematic Review and Meta-Analysis

2025· article· en· W7114806939 on OpenAlexaboutno aff

Bibliographic record

VenueThe American Journal of Gastroenterology · 2025
Typearticle
Languageen
FieldMedicine
TopicIntestinal and Peritoneal Adhesions
Canadian institutionsnot available
Fundersnot available
KeywordsComplicationConservative managementObservational studyOdds ratioBowel obstructionRandomized controlled trialMeta-analysisStudy heterogeneityIncidence (geometry)

Abstract

fetched live from OpenAlex

Introduction: Adhesive small bowel obstruction (ASBO) is one of the most common reasons for hospitalization due to intestinal obstruction. While conservative management is typically the initial approach in clinically stable patients, it is associated with high recurrence rates. However, considerable variability exists in clinical practice. We conducted a systematic review and meta-analysis (SRMA) comparing surgical versus conservative management of ASBO, focusing on recurrence and complication outcomes. Methods: The SRMA was conducted in accordance with PRISMA guidelines. Data on ASBO recurrence and complication rates were extracted from studies that met predefined inclusion criteria. Risk of bias was evaluated using the Cochrane Risk of Bias Tool (RoB 1) for randomized controlled trials (RCTs) and the Newcastle-Ottawa Scale (NOS) for observational studies. Odds ratios (ORs) with 95% confidence intervals (CI) was calculated using random-effect models, and heterogeneity was assessed using the I² statistic. Results: A total of 10 comparative studies encompassing 46,212 patients were included in the analysis. Surgical management was associated with a significantly lower risk of recurrence compared to conservative management (OR: 0.52; 95% CI: 0.38–0.70; P < 0.0001), despite notable heterogeneity (I² = 85%). While the incidence of overall complications appeared higher in the surgical group, this difference did not reach statistical significance (OR: 2.23; 95% CI: 0.92–5.40; P = 0.08), with moderate heterogeneity observed (I² = 65%). These findings suggest that surgical intervention may be preferable in reducing long-term recurrence, without a definitive increase in short-term complication rates. Conclusion: ASBO is a frequent complication of prior abdominal surgery, resulting from fibrous intra-abdominal adhesions. These findings underscore an important clinical consideration: while surgery may offer superior recurrence prevention, it does not appear to significantly increase complication risk. Management strategies should therefore be individualized, balancing patient stability, surgical history, and institutional resources to optimize outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.181
Threshold uncertainty score0.298

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.279
Teacher spread0.260 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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