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Record W7115165637 · doi:10.7759/cureus.99300

Comparing the Effects of Age, Sex, and Extremity Fracture Location on Continuous Intracranial Pressure (ICP) Measurements in Trauma Patients

2025· article· en· W7115165637 on OpenAlexaff

Bibliographic record

VenueCureus · 2025
Typearticle
Languageen
FieldMedicine
TopicMuscle and Compartmental Disorders
Canadian institutionsDalhousie UniversityMcGill University
Fundersnot available
KeywordsForearmCohortProspective cohort studyBlood pressureTibiaCohort studyIntracranial pressureMean arterial pressure

Abstract

fetched live from OpenAlex

Background Baseline data for extremity compartment pressure after trauma have only been looked at in small cohorts with historically inaccurate technology. Newer technology has enabled continuous, accurate pressure monitoring for the diagnosis of acute compartment syndrome (ACS). This study used data from prospective cohort trials with modern pressure sensors to examine baseline pressure values. Particularly, there was a comparison of the effects of age, sex, and fracture location on continuous trend behaviors in extremity trauma patients. Methodology Intracompartmental pressures (ICPs) from 129 non-ACS trauma patients with extremity fractures were examined. The trends in patients were analyzed with respect to age, sex, and anatomical fracture location. Results Younger patients exhibited higher mean ICPs compared to older patients at all time points. Both groups experienced the same rates of decline in pressure over time from trauma. Both older and younger patient groups experienced a steady linear decrease in pressure over the course of monitoring. The younger age group had a decrease of 0.202 mmHg per hour (y = 26.4 - 0.202x), and the older age group showed the same rate of decrease (y = 23.9 - 0.202x). Males and females initially had similar ICPs, but females showed a steeper decline over time, with the pressure in the female group decreasing at a mean rate of 0.303 mmHg/hour compared to 0.163 mmHg/hour in the male group. Tibia fractures were associated with a higher initial pressure and steeper declines in ICP compared to forearm fractures. Conclusions There are variances for continuous ICP measurements associated with age, sex, and fracture location in trauma patients who do not develop ACS. Continuous ICP monitoring offers a better understanding of pressure trends, allowing for more accurate and individualized assessments. Recognizing these trends is crucial in ACS assessment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.020
Threshold uncertainty score0.311

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.268
Teacher spread0.248 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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