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Proposing the ValvUS approach: integrating bedside tests and ultrasonography for severe valvular heart disease diagnosis

2025· article· en· W7115922250 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueEinstein (São Paulo) · 2025
Typearticle
Languageen
FieldMedicine
TopicUltrasound in Clinical Applications
Canadian institutionsUniversité Laval
Fundersnot available
Keywordsvalvular heart diseaseContext (archaeology)DiseaseChest radiographHeart diseaseCardiac UltrasoundUltrasonographyModalities

Abstract

fetched live from OpenAlex

Valvular heart disease is increasingly prevalent, and bedside confirmation or exclusion of severe disease is needed to enable a rapid and cost-effective diagnostic workup. The physical examination skills of clinicians are insufficient for accurate diagnosis, making complementary tests generally necessary. Despite being commonly requested, electrocardiography and chest radiography present low positive and negative likelihood ratios. Incipient studies involving artificial intelligence have shown promising opportunities to support the diagnosis. In addition, solid current evidence demonstrates that point-of-care ultrasound enhances bedside diagnosis of several cardiovascular conditions. Echocardiographic skills can be acquired after only a few hours of training, which encourages routine bedside use with handling equipment. Despite the routine use of sonography in emergencies, large-scale simplified screening protocols for valvular disease remain lacking. Therefore, improving the accuracy of valvular heart disease diagnosis by integrating all bedside modalities needs to be better understood. We propose a simple, reproducible five-step point-of-care ultrasound protocol for diagnosing valvular heart disease (the ValvUS approach), applicable to all patients. The proposed visual assessment involves evaluating valvular movement, thickness, regurgitant flow, aliasing, and chamber dimensions. This evaluation should be interpreted in the context of traditional clinical probability to ensure the most accurate bedside diagnosis. Typical findings of severe valvular disease on electrocardiography and chest radiography, and particularly on point-of-care ultrasound, may improve the accuracy of bedside diagnosis after clinical assessment in the near future.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.097
Threshold uncertainty score0.736

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.326
Teacher spread0.299 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it