MétaCan
Menu
Back to cohort
Record W7116121471 · doi:10.2147/ccid.s541845

CaSMO Recommendations for Prevention and Treatment of Cutaneous Adverse Events Related to Cancer Therapies in Darker Skin Phototypes

2025· article· en· W7116121471 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenueClinical Cosmetic and Investigational Dermatology · 2025
Typearticle
Languageen
FieldMedicine
TopicNonmelanoma Skin Cancer Studies
Canadian institutionsMcGill University Health CentreLynde Centre for DermatologyUniversité LavalMcGill UniversityHôtel-Dieu de QuébecCentre hospitalier universitaire de QuébecPrincess Margaret Cancer CentreCégep de LévisRoyal College of Physicians and Surgeons of CanadaUniversity of Toronto
Fundersnot available
KeywordsAdverse effectSkin cancerErythemaCancerSkin careClinical PracticeHyperpigmentationPatient care

Abstract

fetched live from OpenAlex

The Canadian Skin Management in Oncology (CaSMO) project has expanded its practical recommendations to address cancer therapy-related cutaneous adverse events (CAEs) in patients with diverse skin phototypes, particularly those with darker skin phototypes. This initiative responds to growing awareness of the underrepresentation of non-White populations in cancer research, clinical trials, and dermatologic literature. The guidelines emphasize that CAEs often present differently in individuals with darker skin phototypes, where common clinical signs such as erythema or inflammation may be subtle, atypical, or altogether absent. These diagnostic challenges can lead to delayed recognition, undertreatment, or even misdiagnosis of skin toxicities, increasing the risk of long-term complications such as post-inflammatory hyperpigmentation (PIH) and scarring. Improved clinician awareness of these variations is essential for ensuring timely and equitable management of CAEs across all skin phototypes. The paper presents practical guidance for CAE prevention and management tailored to diverse skin types, including skincare, sun protection, and treatment of pigmentary changes. It also outlines the need for personalized skincare based on individual preferences and physiological differences. The authors advocate for improved clinician education, more inclusive clinical trials, and culturally sensitive care approaches to reduce inequities in oncology dermatology. The article concludes by calling for better representation, research, and resources to support equitable care for patients with skin diversity in Canada.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.029
Threshold uncertainty score0.316

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.058
GPT teacher head0.418
Teacher spread0.359 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it