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Record W7116736776 · doi:10.1136/bmj-2025-085718

AMSTAR-PF: a critical appraisal tool for systematic reviews of prognostic factor studies

2025· article· en· W7116736776 on OpenAlexaff
Michael L Henry, Neil E O’Connell, Beverley Shea, Lotty Hooft, Johanna A A Damen, Nicole Skoetz, Sarah B. Wallwork, G Lorimer Moseley

Bibliographic record

VenueBMJ · 2025
Typearticle
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsBruyèreUniversity of Ottawa
FundersBirmingham Biomedical Research CentreUniversity Hospitals Birmingham NHS Foundation TrustNational Health and Medical Research CouncilMedical Research CouncilNational Institute for Health and Care ResearchAustralian Government
KeywordsCritical appraisalSystematic reviewQuality (philosophy)MEDLINEMeta-analysisImpact factor

Abstract

fetched live from OpenAlex

The ability to predict the onset or natural history of an illness, or how people may respond to a treatment, guides clinical decision making. These predictions are commonly based on prognostic factors: clinical, patient, or societal variables that are identified as being predictive of a certain future outcome. Prognostic factor research has increased across fields, with a subsequent increase in the number of systematic reviews of prognostic factors studies. Understanding the quality of such prognostic factor reviews is essential for confidence in their findings, but there is no quality appraisal instrument to specifically assess systematic reviews of prognostic factor studies. A MeaSurement Tool to Assess systematic Reviews of Prognostic Factor studies, AMSTAR-PF, has been developed to fill this gap.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.145
metaresearch head score (Gemma)0.471
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Evaluation · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.855
Threshold uncertainty score0.766

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1450.471
Meta-epidemiology (narrow)0.0070.004
Meta-epidemiology (broad)0.0180.026
Bibliometrics0.0280.028
Science and technology studies0.0030.003
Scholarly communication0.0080.007
Open science0.0050.009
Research integrity0.0040.007
Insufficient payload (model declined to judge)0.0860.008

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.794
GPT teacher head0.640
Teacher spread0.154 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
DomainEvaluation
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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