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Record W7116798224 · doi:10.64898/2025.12.20.695708

Exogenous auxins for proline regulation in heat-stressed plants

2025· article· W7116798224 on OpenAlexaff
Abdussabur M. Kaleh, Joann K. Whalen

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typearticle
Language
FieldAgricultural and Biological Sciences
TopicPlant-Microbe Interactions and Immunity
Canadian institutionsMcGill University
Fundersnot available
KeywordsAuxinProlineCrosstalkCatabolismAbscisic acidOsmolyteProline dehydrogenaseAbiotic stressMetabolism

Abstract

fetched live from OpenAlex

Abstract Microbial indole-3-acetic acid (IAA) has long been recognized as a driver of plant growth and developmental plasticity. Recent studies show that microbial IAA production is sustained or even enhanced at elevated temperatures, suggesting that microbial auxins may contribute to plant thermotolerance by stabilizing auxin signalling and supporting metabolic adaptation. Here, we synthesize emerging molecular and physiological evidence linking microbial IAA to proline turnover during thermomorphogenesis. We propose that microbial IAA establishes a regulatory window in which proline metabolism transitions between early osmoprotective synthesis and later catabolism that fuels elongation and redox balance. This integration involves crosstalk between the HSP90-TIR1 auxin perception module, heat-responsive MPK-IAA8 signalling, mitochondrial redox regulators (SSR1, HSCA2), and hormonal interactions with abscisic acid and ethylene. We outlined four mechanistic hypotheses and associated experiments to test how microbial IAA modulates proline homeostasis. This framework highlights microbial auxins as metabolic integrators during heat stress and provides a conceptual basis for leveraging auxin-producing microbes to enhance plant resilience under global warming. Highlight Microbial auxins modulate the proline cycle during heat stress by integrating hormonal, redox, and mitochondrial signals, offering a mechanistic framework for how microbial IAA enhances thermomorphogenesis and plant heat resilience.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.223
Teacher spread0.206 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venuebioRxiv (Cold Spring Harbor Laboratory)→Same topicPlant-Microbe Interactions and Immunity→French-language works237,207→