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Record W7116837706 · doi:10.1007/s12630-025-03055-6

Organ and tissue donation and transplantation in people who identify as Two-Spirit, gay, bisexual, transgender, queer, intersex, and more: a Canada-wide cross-sectional community survey

2025· article· en· W7116837706 on OpenAlexafffundabout
Murdoch Leeies, David Collister, Julie Ho, Carmen Hrymak, Emily Christie, Sonny Dhanani, Warren Fingrut, Jacquie Gahagan, Karen Doucette, Tzu‐Hao Lee, Stephen Brodovsky, Ken Sutha, Cameron T. Whitley, Ben Klassen, Kimia Rohani, Chris Draenos, Nathan J. Lachowsky

Bibliographic record

VenueCanadian Journal of Anesthesia/Journal canadien d anesthésie · 2025
Typearticle
Languageen
FieldMedicine
TopicOrgan Donation and Transplantation
Canadian institutionsCanadian Nutrition SocietyMount Saint Vincent UniversityUniversity of VictoriaCanadian Cardiovascular SocietyChildren's Hospital of Eastern OntarioCanadian Thoracic SocietyUniversity of OttawaCommunity Based Research CentreUniversity of AlbertaUniversity of ManitobaResearch Manitoba
FundersRoyal College of Physicians and Surgeons of Canada
KeywordsTissue DonationOrgan donationTransplantationDonationRisk assessmentTissue bank

Abstract

fetched live from OpenAlex

PURPOSE: Inequities for sexual- and gender-minoritized (SGM) populations in organ and tissue donation and transplantation (OTDT) have been identified. We aimed to understand the awareness and attitudes of community members who are SGM regarding current SGM-relevant policies, policy gaps, and policy alternatives in Canadian OTDT systems. METHODS: We conducted an online, cross-sectional, Canada-wide survey of members of the Two-Spirit, gay, bisexual, transgender, queer, intersex and more (2SGBTQI+) communities (June-September 2024). Questionnaire development adhered to current survey science recommendations. We present descriptive data as counts and proportions. RESULTS: We analyzed responses from a convenience sample of 2,276 participants from across Canada. Most participants self-identified as White cisgender gay men. Prior to questionnaire completion, only 17% (257/1,497) of participants were aware that men who have sex with men are considered "increased infectious risk donors" in OTDT and cannot donate tissues, and 20% (302/1,512) were aware that they may only donate organs if the benefit to the recipient is deemed to outweigh the risk. Of the respondents, 18% (270/1,535) did not realize that potential donors are screened on the basis of sex assigned at birth as opposed to self-identified gender identity. On average, 23% (1,406/6,084) of participants perceived these policies as nondiscriminatory. Of the respondents, 60% (1,865/3,115) supported gender-neutral, behavior-focused donor risk assessments that were data-driven. Most participants reported a willingness to donate organs (79%; 1,237/2,276) and tissues (72%; 1,123/2,276) after death. CONCLUSIONS: People in Canada who self-identify as 2SGBTQI+ perceived current OTDT policies to be discriminatory and in need of equitable revision. Evidence-based behavioral and gender-neutral donor risk criteria were preferred over identity-based criteria. The majority of survey participants who identify as SGM were willing to donate organs and tissues despite current system inequities. Health Canada should revise current donor risk assessment criteria to ensure they are data-driven and optimize access and safety to OTDT in Canada.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.030
Threshold uncertainty score0.063

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0030.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.313
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractyes

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