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Record W7117104181 · doi:10.1177/09544119251403379

Structural validation of novel bileaflet mechanical heart valve hinge mechanism

2025· article· en· W7117104181 on OpenAlexafffund
Dylan Goode, Usama Ishtiaq, Dahlia Mohammadi, Hadi Mohammadi

Bibliographic record

VenueProceedings of the Institution of Mechanical Engineers Part H Journal of Engineering in Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicCardiac Valve Diseases and Treatments
Canadian institutionsUniversity of British Columbia, Okanagan CampusUniversity of British Columbia
FundersUniversity of British Columbia
KeywordsHingeFinite element methodvon Mises yield criterionStress (linguistics)DurabilityMechanism (biology)Size effect on structural strength

Abstract

fetched live from OpenAlex

The structural performance of hinges in mechanical heart valves (MHVs) is essential for durability and reliability. This study evaluates the iValve, a novel bileaflet MHV, using advanced finite element method (FEM) simulations to assess its hinge design under physiological and supra-physiological conditions. The hinge design aims to minimize stress concentrations, reduce wear, and enhance durability compared to conventional valves. A detailed 3D FEM model, incorporating precise hinge geometry, was developed to analyze stress distribution, deformation, and potential failure zones. While our study uses a quasi-static finite element approach, and thus does not capture full dynamic or fluid-structure interactions, it evaluates peak physiological loading conditions representative of the cardiac cycle. The results show a lower and more uniform stress distribution in the iValve compared to conventional bileaflet MHVs, suggesting reduced stress concentrations and potentially improved fatigue life. The model was validated against experimental data from in vitro flow simulators, ensuring accurate representation of the hemodynamic forces during the cardiac cycle. Results show that the iValve's hinge design achieves superior stress distribution with significantly lower peak von Mises stresses than traditional designs. Optimized materials and geometric features reduce the risk of fatigue and wear, while high-cycle fatigue simulations confirmed minimal deformation, demonstrating suitability for extended use. This study highlights the role of FEM in advancing MHV design by balancing mechanical performance with physiological compatibility. The iValve addresses hinge failure and thrombus risks, offering a durable, anticoagulation-free solution.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.302
Teacher spread0.284 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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Same venueProceedings of the Institution of Mechanical Engineers Part H Journal of Engineering in MedicineSame topicCardiac Valve Diseases and TreatmentsFrench-language works237,207