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Record W7117320435 · doi:10.1002/alz70858_103696

To live and die well with neurocognitive disorders

2025· article· en· W7117320435 on OpenAlexaffabout
Félix Pageau, Sonia Bélanger, Jeane Day, Marie Christine Le Bourdais, Paolo Vitali, Ziad Nasreddine, Guy Lacombe, Thomas Tannou

Bibliographic record

VenueAlzheimer s & Dementia · 2025
Typearticle
Languageen
FieldMedicine
TopicPalliative Care and End-of-Life Issues
Canadian institutionsCentre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-MontréalMinistère de la Santé et des Services Sociaux (Québec)Centre Hospitalier Universitaire de SherbrookeMcGill University Health CentreAlzheimer Society of CanadaUniversité Laval
Fundersnot available
KeywordsAutonomyLegalizationContext (archaeology)NeurocognitiveEthical issuesPremiseAssisted suicideBioethicsMedical ethics

Abstract

fetched live from OpenAlex

The end of life in Major Neurocognitive Disorder (MND) is often shaped by a range of medical complications. These can include aspiration pneumonia, hip fractures, subdural hemorrhages, untreated cancer, or pyelonephritis. Regardless of the cause, the provision of appropriate, compassionate care remains a critical element. In Quebec, the recent legalization of medical assistance in dying (MAiD) through advance requests for individuals with MND introduced new dimensions to how these individuals approach death. What are the ethical implications of this change? In this presentation, we aim to explore how death occurs from MND, specifically in the context of Quebec in 2025, and the ethical dilemmas associated with this shift. To understand these ethical concerns, it is also crucial to examine what constitutes a "good death" in MND. A "good death" is not only about the medical management of end-of-life symptoms but also about the opportunity to maintain dignity, receive emotional support, and, for some, exercise personal autonomy in decision-making. We will discuss these concepts and present an article we have written and published in the scientific journal Mortality. This article discusses the difficult choices faced by individuals with MND: whether to die quickly and painlessly or to take time to say goodbye to loved ones-a decision that is often fraught with emotional and ethical challenges. These issues were raised during semi-structured interviews conducted by Dr. Pageau, who gathered data as part of a research project on the determination of care levels in geriatric patients in Quebec. The interviews provided valuable insights into the personal, social, and ethical dimensions of end-of-life decision-making for people with MND. We will present the results of this study to help foster an ethical discussion about the complex issues surrounding care and the dying process for individuals with neurocognitive disorders.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.288
Threshold uncertainty score0.573

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0070.004
Scholarly communication0.0020.002
Open science0.0010.002
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.045
GPT teacher head0.353
Teacher spread0.308 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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