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Record W7117323699 · doi:10.7759/cureus.100135

Capgras Syndrome Triggered by Marital Separation: A Rare Case of Trauma-Induced Delusional Misidentification

2025· article· en· W7117323699 on OpenAlexaboutno aff
Ali Z Ansari, Fizza Ahmed, Pho Q Doan, Abdul Ahad Siddiqi, Sahar Najmus Hafeez

Bibliographic record

VenueCureus · 2025
Typearticle
Languageen
FieldNeuroscience
TopicFace Recognition and Perception
Canadian institutionsnot available
Fundersnot available
KeywordsCapgras SyndromeContext (archaeology)Delusional disorderInterpersonal communicationNeurological examinationPsychopathologyDaughterDelusionPsychiatric history

Abstract

fetched live from OpenAlex

Capgras syndrome is a rare psychiatric condition classified under delusional misidentification syndromes, characterized by the belief that a familiar person has been replaced by an identical impostor. Although it is most commonly observed in association with schizophrenia, neurodegenerative diseases, or structural brain lesions, it may also arise in the context of acute psychological trauma or severe emotional disturbance. We present the case of a 46-year-old African American woman with no prior psychiatric or neurological history who presented to an outpatient psychiatry clinic accompanied by her sister, with a sudden onset of delusional misidentification involving her husband and adolescent daughter. The symptoms developed shortly after the unexpected discovery of her husband's extramarital affair and his decision to initiate divorce proceedings, events which she described as profoundly destabilizing. Within days, she became convinced that both her husband and daughter had been replaced by impostors who were physically identical but emotionally unfamiliar, leading to avoidance behaviors, interpersonal conflict, and significant functional impairment. The patient denied hallucinations or other psychotic symptoms, and cognitive screening with the Montreal Cognitive Assessment (MoCA) was within normal limits (28/30). A comprehensive medical and neurological evaluation, including laboratory workup and bedside neurological examination, revealed no abnormalities, and although neuroimaging and electroencephalography (EEG) were declined by the patient, there were no clinical indications of organic pathology. The clinical picture was most consistent with delusional disorder with features of Capgras syndrome in the context of acute psychological trauma. Treatment was initiated with low-dose risperidone, gradually titrated to 2 milligrams per day, alongside trauma-focused psychotherapy focused on narrative reconstruction and emotional integration. Over a three-month period, the patient exhibited marked improvement in insight and reduction in the intensity of her delusional beliefs, eventually acknowledging that her perceptions may have been distorted by emotional distress. This case demonstrates a rare but clinically important presentation of Capgras syndrome triggered by acute psychosocial trauma in the absence of psychosis or neurological disease. It highlights how severe emotional stress can lead to a functional disconnect between facial recognition and emotional familiarity, resulting in delusional misidentification even in high-functioning individuals. Prompt psychiatric treatment combining antipsychotic medication and trauma-focused psychotherapy can support recovery and help prevent further psychological decline.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.003
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0020.002
Scholarly communication0.0010.001
Open science0.0010.002
Research integrity0.0040.002
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.047
GPT teacher head0.343
Teacher spread0.296 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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