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Record W7117418527 · doi:10.64898/2025.12.17.25342104

Virtual Reality applied to Post-Stroke Rehabilitation: design and development of the NeuroRehab VR Software

2025· article· W7117418527 on OpenAlexaff
Mercedes Gil-Rodríguez, Amaya-Pascasio Laura, Alba Hernandez-Martinez, Marta Rodríguez-Camacho, Manuel Fernández-Escabías, Sofía Carrilho-Candeias, Máriam Ramos-Teodoro, Andrea Rodríguez-Solana, Andrea Orellana-Jaen, Rodrigo Fernandez-Escabias, Maria Tomas-Garcia, Belén Castro-Ropero, Laura Del Olmo-Iruela, María Isabel López López, Karol J. García-Luna, Fernando Morales-Marquez, Silvia Gómez-García, M. Victoria Pérez, Antonio Rodrı́guez-Sánchez, Inmaculada Villegas-Rodríguez, Francisco J. Amaro-Gahete, Alberto Soriano-Maldonado, Martinez-Sanchez Patricia

Bibliographic record

VenuemedRxiv · 2025
Typearticle
Language
FieldMedicine
TopicStroke Rehabilitation and Recovery
Canadian institutionsHealth Research Foundation
FundersAgencia Estatal de InvestigaciónEuropean CommissionEuropean Social FundUniversidad de AlmeríaMinisterio de Ciencia, Innovación y Universidades
KeywordsVirtual realityMultidisciplinary approachSoftwareFocus groupRehabilitationThematic analysisQuality (philosophy)Augmented reality

Abstract

fetched live from OpenAlex

ABSTRACT Objective To describe the design and development of NeuroRehab VR, a fully immersive, specific and gamified virtual reality (VR) software aimed at improving the quality of life and reducing disability in post-stroke patients. Methods A public-private collaborative research project was carried out between 2022 and 2024 by a multidisciplinary and multicenter team comprising neurologists, rehabilitation specialists, physiotherapists, exercise and sport sciences professionals and members of the company Dynamics VR Rehab, including engineers, developers, computer programmers, game designers, and digital artists. The project was structured into three phases: preproduction, production, and postproduction, with periodic focus group meetings and testing sessions with patients in the subacute phase of stroke held every one to two months. Results In the Preproduction phase, the multidisciplinary team discussed the initial concepts and, using the SCRUM methodology together with feedback from pilot patients, developed the software design. In this process, three thematic environments (i.e., home, nature, and science fiction) were established, along with five activity types targeting upper limb rehabilitation: fine motor skills, gross motor skills, balance, rhythmic movements, and movement speed. The software incorporated fully immersive VR, advanced hand tracking technology, and adaptive gamification elements. During the Production phase, these components were implemented and consolidated into a functional prototype. Finally, in the post-production phase, several adjustments were made after identifying minor issues, with the aim of improving activity responsiveness and refining the user experience for both patients and clinicians. Conclusion NeuroRehab VR represents a promising tool to be integrated into post-stroke rehabilitation programs and is being tested though a clinical trial. Moreover, this public-private, multidisciplinary, and multicenter collaboration model constitutes an effective framework for the design and development of technologically driven solutions applicable to clinical rehabilitation settings.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.002
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.269
Teacher spread0.252 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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