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Record W7117448427 · doi:10.1093/jas/skaf398.030

36 Impact of feeding different selenium (Se) sources to pregnant and lactating ewes on lamb Se enrichment and serum biochemistry profiles

2025· article· en· W7117448427 on OpenAlexaff
Nicole Moran, Rebecka A. Sadler, Umesh K. Shandilya, Niel A. Karrow

Bibliographic record

VenueJournal of Animal Science · 2025
Typearticle
Languageen
FieldNursing
TopicSelenium in Biological Systems
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsSeleniumLactationGlutathione peroxidaseGestationTriiodothyroninePregnancyWeaningCreatine

Abstract

fetched live from OpenAlex

Abstract Abstract: Introduction Global pre-weaning lamb mortalities have remained above 10%, a detriment to farm profits. Selenium (Se) is a trace mineral vital to several functions in sheep. Se supplementation during late pregnancy and lactation, particularly organic Se supplementation, may produce more robust lambs. Objective To determine how differences in maternal Se supplementation impact lamb health within 10 days postpartum (ppd 10). Methods Ewes (n = 110) were enrolled in a feeding trial from gestation day (gd) 110 to ppd 10, and supplemented with either no Se, 0.3 mg/day inorganic Se, or 0.3 or 0.6 mg/day organic Se. Lambs only received Se via maternal nursing. Lamb serum was collected on ppd 0, 2, and 10 to assess maternal transfer of Se, and muscle samples were collected on ppd 10 to assess lamb Se stores. Serum glutathione peroxidase (GPx) levels, thyroid hormone triiodothyronine (T3) levels, and a complete ovine 23-parameter biochemistry panel were assessed on ppds 0 and 10. Results Maternal organic Se supplementation significantly increased Se levels in lamb serum (P < 0.0001) and muscle (P < 0.0001) as compared to other treatments. Organic Se supplementation significantly increased GPx activity at birth (P > 0.001), but T3 levels were not affected. From the biochemical panel, serum levels of non-esterified fatty acid, potassium, chloride, albumin, total bilirubin, creatine kinase, aspartate aminotransferase, and glutamate dehydrogenase showed significant treatment differences. Conclusions Organic Se supplementation to ewes during late gestation and lactation improved lamb Se status and antioxidant capacity at birth. Other serum biochemistry parameters were only marginally affected by Se treatment. (Supported by NSERC 401814)

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.300
Threshold uncertainty score0.368

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.324
Teacher spread0.301 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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