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Record W7117568236 · doi:10.31579/2578-8949/189

The Role of Antibiotics in Climate Change

2025· article· W7117568236 on OpenAlex
Rehan Haider

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

fundA Canadian funder is recorded on the work.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueDermatology and Dermatitis · 2025
Typearticle
Language
FieldEnvironmental Science
TopicPharmaceutical and Antibiotic Environmental Impacts
Canadian institutionsnot available
FundersUniversity of Calgary
KeywordsGreenhouse gasClimate changeSustainabilityAntibioticsAntibiotic resistanceSustainable developmentCarbon footprintPublic health

Abstract

fetched live from OpenAlex

Antibiotics, widely used to combat infections, have an unintended impact on the environment, contributing to climate change through their production, application, and disposal. The pharmaceutical sector is a significant source of greenhouse gas (GHG) emissions and other pollutants throughout the antibiotic manufacturing process, exacerbating global warming. Additionally, improper antibiotic disposal leads to environmental contamination, promoting antimicrobial resistance (AMR) and disrupting microbial ecosystems essential for the carbon and nitrogen cycles. Moreover, their use in livestock increases methane emissions and soil degradation. Addressing this dual challenge—AMR and climate change—requires sustainable practices in antibiotic production, distribution, and waste management. Strategies such as implementing green chemistry in drug manufacturing, exploring alternative therapies, and enhancing wastewater treatment processes can significantly reduce pharmaceutical pollution. Policies must focus on minimizing antibiotic misuse while mitigating the environmental consequences of pharmaceutical waste. Cross-disciplinary collaboration is essential to tackle the interconnected challenges posed by antibiotics and climate change. Developing sustainable solutions will help maintain both public health and ecological balance while reducing the long-term environmental footprint of antibiotic usage.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.116
Threshold uncertainty score0.721

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.267
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it