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Record W7117671422 · doi:10.1111/2041-210x.70199

Early warning signal for river‐borne diseases with almost no data

2025· article· en· W7117671422 on OpenAlexaffabout
Pouria Ramazi, Prajwal Bende, Arezoo Haratian, R. Greiner, Mark A. Lewis

Bibliographic record

VenueMethods in Ecology and Evolution · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMyxozoan Parasites in Aquatic Species
Canadian institutionsNorthern Alberta Institute of TechnologyUniversity of VictoriaUniversity of AlbertaUniversity of Calgary
Fundersnot available
KeywordsHidden Markov modelWarning systemCovariateMarkov chainReceiver operating characteristicExploitOutbreakTest dataMarkov model

Abstract

fetched live from OpenAlex

Abstract Effective management of emerging river‐borne diseases requires early prediction of pathogen spatial distributions. However, data on pathogen locations are notoriously rare in the beginning of disease outbreaks and insufficient to feed existing predictive models. We extended hidden Markov models (HMM) to exploit detailed spatially structured data on environmental covariates that are readily available for many aquatic systems, augmented by arbitrarily sparse spatial data on actual pathogen occurrence, to predict pathogen distribution over large geographical scales. The extended HMM predicted the spread of whirling disease in the Oldman River, Canada, with 0.7 area under the receiver operating characteristic curve (AUC) in the absence of any disease test result, provided that the status of a single pixel can be estimated correctly. The AUC increased with the number of used test results, until it reached 0.9 when 100 test results were used. The model has the potential to provide early warning signals for emerging diseases prior to, or at the early stages of, their emergence in a river.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.215
Threshold uncertainty score0.369

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.361
Teacher spread0.342 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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