IMPACT OF GASTROINTESTINAL TRACT DISEASES ON CARIES DEVELOPMENT, PROGRESSION, AND THE EFFECTIVENESS OF ORTHOPEDIC PROSTHETIC TREATMENT
Bibliographic record
Abstract
The relevance of the study is due to growing evidence of a close relationship between gastrointestinal pathology and the development of dental diseases, including caries and complications of removable and fixed prosthetics. The aim of the study is to systematize and analyze the scientific literature on modern views on the influence of gastrointestinal pathology on the development and course of caries, as well as on removable and fixed prosthetics with orthopedic structures. The literature review was carried out by searching the PubMed, Web of Science, Scopus and Google Scholar databases using MeSH terms. The results of the analysis indicate that the main pathophysiological mechanism of the negative impact of gastrointestinal pathology is a change in the acid-base balance and composition of saliva, which leads to enamel demineralization, reduced adhesion of dental materials, increased risk of secondary caries, prosthetic stomatitis and candidiasis. Gastroesophageal reflux is associated with frequent episodes of acid exposure of enamel and the formation of erosions, Helicobacter pylori-associated gastritis reduces the buffer capacity of saliva and impairs its antibacterial properties, and chronic inflammatory bowel diseases cause a decrease in the bioavailability of calcium and other trace elements. It has been established that such changes significantly affect the success of denture fixation, the stability of orthopedic structures and the frequency of complications in the post-prosthetic period. The findings confirm the need for an interdisciplinary approach to treatment, which includes a preliminary gastroenterological examination, determination of saliva pH and composition, remineralizing therapy, and the use of materials with increased resistance to acid action. Prospects for further research include conducting multicenter clinical trials to develop unified international recommendations for orthopedic treatment of patients with concomitant gastrointestinal pathologies.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.014 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.002 |
| Bibliometrics | 0.004 | 0.003 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.002 | 0.001 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.004 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".