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Record W7124538523 · doi:10.1093/cercor/bhaf331

The inferior frontal sulcus in the chimpanzee brain: morphological examination and association with oro-facial communication

2025· article· en· W7124538523 on OpenAlexafffund
Erika Nolan, Claude Lepage, William D. Hopkins, Michael Petrides

Bibliographic record

VenueCerebral Cortex · 2025
Typearticle
Languageen
FieldNeuroscience
TopicHemispheric Asymmetry in Neuroscience
Canadian institutionsMcGill UniversityMontreal Neurological Institute and Hospital
FundersCanadian Institutes of Health Research
KeywordsAssociation (psychology)SulcusLateralization of brain functionBrain morphometryMorphology (biology)Human evolutionBrain mappingHuman brainRight hemisphere

Abstract

fetched live from OpenAlex

There has been considerable interest in the neuroanatomical homologue of Broca's region in nonhuman primates, particularly in our phylogenetically closest relative the chimpanzee (Pan troglodytes), to further our understanding of the evolution of language in hominins. The inferior frontal sulcus (ifs) is a critical landmark below which lie language production areas in the language-dominant hemisphere of the human brain, and its homologue is found in the chimpanzee brain. The present study examined the variability in the morphology of the ifs in 73 chimpanzee brains (ie 146 hemispheres). Examination was carried out on surface reconstructions derived from in vivo 3 T magnetic resonance imaging scans, which permitted detailed intra-sulcal assessment. Based on the connections formed by the ifs and adjacent sulci, two frequent and three less frequent morphological types were identified. The average location and spatial variability of the ifs were quantified in the form of spatial surface probability maps. Relationships were also established between specific morphological features of the ifs in the left hemisphere and oro-facial communication abilities, as measured by attention-getting sound production. These findings refine our knowledge of prefrontal sulcal organization in hominids and offer valuable insights into the structural blueprints that supported the emergence of speech in humans.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.359
Threshold uncertainty score0.442

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.262
Teacher spread0.248 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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