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Record W7124669364

[A Case of Oligometastatic Recurrent Colorectal Liver Metastasis Effectively Treated with Stereotactic Body Radiation Therapy].

2025· article· ja· W7124669364 on OpenAlexaff
Nobutsugu Takei, Yasuji Seyama, Hiroko Okinaga, Masanao Kurata, Daisuke Nakano, Takuya Shimizuguchi, Mizuka Suzuki, Shinichiro Horiguchi

Bibliographic record

VenuePubMed · 2025
Typearticle
Languageja
FieldMedicine
TopicHepatocellular Carcinoma Treatment and Prognosis
Canadian institutionsPancreas Centre (Canada)
Fundersnot available
KeywordsRadiation therapyRadiosurgeryMetastasisColorectal cancerRadiation dose
DOInot available

Abstract

fetched live from OpenAlex

BACKGROUND: Colorectal cancer liver metastasis(CRLM)is commonly managed with surgery or systemic chemotherapy. However, alternative treatments are needed for patients who are not candidates for these standard therapies. Stereotactic body radiation therapy (SBRT) has shown promising results in terms of local control. CASE: A 78-year-old woman underwent low anterior resection for rectal cancer(cStage Ⅲc)followed by 3 hepatic resections for metachronous CRLM. Upon the fourth recurrence, surgery was deemed infeasible due to advanced age, the location of recurrence, and surgical history. Additionally, the patient declined systemic chemotherapy. After multidisciplinary discussion, SBRT(50 Gy in 5 fractions)was chosen as the treatment strategy. RESULTS: The patient tolerated SBRT without adverse events. Post-treatment imaging revealed tumor regression, and serum tumor markers normalized within 4 months. There has been no recurrence to date. She has remained disease-free for 5 years after the initial rectal surgery and 3 years following SBRT. CONCLUSION: SBRT may be a safe and effective alternative for patients with recurrent CRLM who are not candidates for surgery or chemotherapy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0020.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0040.002
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.045
GPT teacher head0.251
Teacher spread0.205 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venuePubMed→Same topicHepatocellular Carcinoma Treatment and Prognosis→French-language works237,207→