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Record W7126195871 · doi:10.1093/jcag/gwaf041

Improving the quality of paracentesis practices in people with advanced cirrhosis in an ambulatory care setting

2025· article· en· W7126195871 on OpenAlexaffabout
Mary Sedarous, Elizabeth Lee, Adam Bishara, Ina Cherepaha-Kantorovich, Amol Verma, Kieran L. Quinn, Gideon M. Hirschfield

Bibliographic record

VenueJournal of the Canadian Association of Gastroenterology · 2025
Typearticle
Languageen
FieldMedicine
TopicSepsis Diagnosis and Treatment
Canadian institutionsInstitute for Work & HealthQueen's UniversityLondon Health Sciences CentreUniversity Health NetworkUniversity of TorontoInstitute of Health Services and Policy Research
Fundersnot available
KeywordsAmbulatoryParacentesisHepatologyData collectionGuidelineSpecialtyCirrhosisHepatorenal syndrome

Abstract

fetched live from OpenAlex

Abstract Background and Aims Spontaneous bacterial peritonitis (SBP) is a lethal complication of decompensated cirrhosis with a 90% mortality rate if untreated. Despite AASLD guidelines, a practice gap exists in fluid cell count (FCC) collection during paracentesis. We initiated a quality improvement (QI) project to increase FCC collection from 78% to 100% in an ambulatory setting between September 11, 2022, and April 17, 2023. Methods We evaluated 233 ambulatory patient encounters for paracentesis procedures at a quaternary care centre in Toronto. A multidisciplinary QI initiative included focused groups, AASLD guideline education, a paracentesis bundle, and workflow streamlining. Descriptive statistics and statistical analyses using run charts and p-charts were conducted via QI Macros. Institutional QI Review Committee approval was obtained. Results Baseline FCC adherence was 78%. Process mapping identified inconsistencies in documentation, label printing, and FCC collection. Bedside paracentesis bundles were introduced, increasing FCC collection marginally to 79.6% with no special cause variation. Subgroup analysis showed FCC collection rates of 100% among RNs/NPs, 97% among residents, and 92% among attending physicians. General hepatology had a 97% collection rate, while specialty hepatology had 40%. The SBP rate was 1.62% (N = 3). Discussion This study highlights a persistent gap in FCC collection during ambulatory paracentesis. Understanding reasons for non-compliance and assessing the FCC collection’s impact on morbidity and mortality in ambulatory settings are next crucial steps to optimize care for this high-risk population.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.017
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.046
Threshold uncertainty score0.091

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.017
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.329
Teacher spread0.305 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

Explore more

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