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Record W7127111231 · doi:10.1177/25739581251376356

Building Consensus Around Adult Autism Diagnostic Assessment: A Mixed-Methods Approach

2025· article· en· W7127111231 on OpenAlexafffund
Charlotte I. Stewardson, Lorelei P. McEwen, Connor M. Kerns

Bibliographic record

VenueAutism in Adulthood · 2025
Typearticle
Languageen
FieldNeuroscience
TopicAutism Spectrum Disorder Research
Canadian institutionsUniversity of British Columbia
FundersSocial Sciences and Humanities Research Council of Canada
KeywordsAutismThematic analysisExcellenceClinical PracticeDelphi methodNiceMental healthMEDLINE

Abstract

fetched live from OpenAlex

Background: Diagnosing autism in adulthood presents several challenges, including scant validated measures, overlapping characteristics with other conditions, and limited information regarding client preferences and experiences. We sought to generate consensus best practice (CBP, i.e., high endorsement or agreement by ≥75%) between expert clinicians and autistic adults around existing clinical practice guidelines (CPGs) and co-develop statements for enhancing practice. Methods: Thirty-five autistic adults and 30 expert clinicians participated in a three-round Delphi survey. Participants rated abbreviated versions of National Institute for Health and Care Excellence CPGs for adult autism diagnosis on importance, feasibility, and acceptability. In Round 1, participants also answered open-ended questions regarding what is currently working well, missing, and in need of improvement in adult autism assessment. We conducted thematic analysis on these open-ended responses to generate co-developed statements. In subsequent rounds, participants reviewed prior round ratings and comments and then re-rated CPGs (on all three metrics) and co-developed statements to generate CBP. They also selected their top five co-developed statements in Round 3. Results: By Round 3, both groups reached CBP on the importance of over 50% of CPGs, covering topics such as having trained professionals and assessing core autism features, mental health, and early development. However, they reached CBP less often on feasibility and acceptability. Clinicians reached CBP more often than autistic adults. Participants also reached CBP on most (24/31) co-developed statements, highlighting priorities like clear communication, neurodiversity-affirming care, and better access to diagnostic assessments. Participants did not reach CBP for informant involvement within the autistic adult group or for multidisciplinary evaluations across groups. Conclusions: While participants supported the importance of many CPGs, further research should address feasibility and acceptability challenges. CBP and co-developed statements may enhance adult autism assessments for both clinicians and autistic adults; however, empirical evaluation in clinical settings will be key.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.310
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.005
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.003
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.372
Teacher spread0.350 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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