Canine multilobular tumour of the bone arising in non-cranial sites: three cases
Why this work is in the frame
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Bibliographic record
Abstract
The multilobular tumour of bone (MTB) is a relatively uncommon tumour. Its biological behaviour may range from benign to malignant. MTB typically affects the canine skull; MTBs arising in non-cranial sites are exceedingly rare.(1) Here we present a series of three such cases, including two tumours arising in non-cranial skeletal (spinal and pelvic) and an extraskeletal one (muscle). Methods and results. The first tumour reported concerned the medial aspect of the left thigh of an eight-year-old female Cocker Spaniel that was presented with a history of acute lameness. The second tumour reported arose on the body of the first lumbar vertebra of a 10-year-old male Labrador, while the third concerned the right tuber ischii region of a 13-year-old female Corgi. Clinical signs varied depending on location. All animals were euthanized upon the owners’ request. metastases were observed on necropsy. In the first case, a large tough white tumour replacing the heads of the vastus medialis and rectus femoris muscles was evident; no local involvement of bone or joint was observed. Histologically, the tumours varied widely but were all characterized by the dominant presence of multiple osteoid-containing lobules that were separated, to a varying degree, by fibrous septae, a feature typical of MTB. The spinal tumour also contained myxoid-like material and had an atypical morphology. MTB may arise in non-cranial and extraskeletal sites.and should be included in the differential diagnosis of osseous tumours arising in such sites.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.002 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it