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Record W7132999198

Bridging the gap: Patient and healthcare professional perspectives on accessing and using cancer genetics services by racialized communities

2025· dissertation· W7132999198 on OpenAlexafffundabout
Sonya Kaur Grewal

Bibliographic record

VenueTSpace · 2025
Typedissertation
Language
FieldBiochemistry, Genetics and Molecular Biology
TopicBRCA gene mutations in cancer
Canadian institutionsInstitute of Health Services and Policy Research
FundersCanadian Institutes of Health ResearchNovo NordiskUniversity of Toronto
KeywordsCancer geneticsMedical geneticsHealth careHarmHealth equityEthnic groupGenetic counselingGenetic testingWorkforce
DOInot available

Abstract

fetched live from OpenAlex

Introduction: Racial and ethnic disparities exist across the entire cancer genetics service pathway. Racialized individuals are less likely to be referred for genetic testing and more likely to receive inconclusive results due to underrepresentation in genomic databases. This limits access to early detection and prevention, high-risk cancer screening, and genetic testing for atrisk relatives, ultimately impacting health outcomes. Limited efforts in Canada to identify racial disparities impedes the development and implementation of appropriate interventions.Aim: To explore the barriers and enablers to accessing and using cancer genetics services by racialized communities. Methods: Semi-structured interviews were conducted with racialized patients and healthcare professionals involved in cancer genetics care across Ontario. Analysis followed an interpretive description approach. Results: 11 patients and 10 healthcare professionals (six genetic counselors, two primary care physicians, one medical geneticist, and one oncologist) were interviewed. Four themes emerged shaping the experiences of racialized communities with cancer genetics services: (1) medical mistrust, (2) structural barriers, (3) family history gaps, and (4) the need for more inclusive care. Both groups described how historical and personal experiences of medical harm and discrimination diminish patient trust and shape their willingness to engage with genetics services. Participants also discussed how the healthcare system’s structure creates multiple barriers to accessing cancer genetics care. Specifically, they noted workforce shortages among primary care physicians and genetics specialists, long wait times for genetic counseling appointments and testing, clinical time constraints, and limited genetics knowledge among patients and referring providers. Participants discussed gaps in family health history, stemming from cultural norms and privacy around illness, geographic separation between relatives, and limited access to health records; reliance on family history for testing eligibility can unintentionally disadvantage racialized communities. Lastly, participants emphasized the need for greater inclusivity in the healthcare system, including workforce diversity, language accessibility, and cultural awareness among healthcare professionals. Conclusion: Multi-level, intersectional barriers exist to accessing cancer genetics services for racialized patients. This work will be used to co-develop interventions to optimize access and reduce disparities.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.017
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.132
Threshold uncertainty score0.262

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0100.017
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0190.007
Scholarly communication0.0060.004
Open science0.0010.010
Research integrity0.0020.004
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.399
Teacher spread0.368 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractyes

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