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Record W7159982221 · doi:10.47739/2475-9406/1010

Burn Patients with TBSA ≤30% Display Whole Blood Hypercoagulablility 14 days’ Post Trauma

2017· article· en· W7159982221 on OpenAlexaff
Christian Lyngsaa Lang, Jais Oliver Berg, Sisse Rye Ostrowski, PärIn­ge­mar Jo­hanson, Liselotte S. Ebbesen

Bibliographic record

VenueResearch at the University of Copenhagen (University of Copenhagen) · 2017
Typearticle
Languageen
FieldMedicine
TopicTrauma, Hemostasis, Coagulopathy, Resuscitation
Canadian institutionsInstitute of Infection and Immunity
Fundersnot available
KeywordsThromboelastographyWhole bloodFibrinogenTotal body surface areaCoagulationThird-Degree BurnProspective cohort studyBurn injury

Abstract

fetched live from OpenAlex

Introduction: The aim of this study was to investigate baseline and 14 days prospective changes in viscoelastic whole blood coagulation by thromboelastography (TEG) in patients with moderate and severe burns corresponding to ≥ 10 % total body surface area (TBSA). Methods: 13 patients with burns ≥ 10% were included in the study. TEG analysis and standard coagulation parameters as APTT, INR, platelet count, and fibrinogen were carried out at admission and the following 14 days. Results: Most TEG variables changed in a hypercoagulable direction the first 2 weeks following burn injury. a values increased (p<0.0004) from post burn day one 54 degrees to 69 degrees’ day seven. MA increased (p<0.05) from 62 mm at day one to 73 mm at day five. K values decreased (p<0.03) from 2.9 minutes at day one to 1.9 minutes at post burn day three. MTG (p<0.005) started at 15994 mm*100/sec at day one and increased to 30549 mm*100/sec at post burn day eight. All remained significant until day 14. R, Ly-30 and TMG did not change in the observation period. In contrast APTT increased (p<0.05) from 25.8 sec. to 30.2 sec. in six days. Fibrinogen increased from 11.55mmol/L to 20.37 mmol/L day six (p<0.05) and INR decreased from 1.17 to 1.05 day five (p< 0.02). Conclusion: Burn patients with TBSA ≤ 30% and who are not subject to surgical intervention are in a hypercoagulable state detected by whole blood viscoelastic haemostatic assays TEG that extended 2 weeks post injury

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.276
Teacher spread0.243 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2017
Admission routes1
Has abstractyes

Explore more

Same venueResearch at the University of Copenhagen (University of Copenhagen)→Same topicTrauma, Hemostasis, Coagulopathy, Resuscitation→French-language works237,207→