ACUTE ORGANOPHOSPHORATE POISONING: CLINICAL, DIAGNOSTIC AND THERAPEUTIC APPROACH
Bibliographic record
Abstract
Organophosphate poisoning is considered pesticides that have the ability to inhibit the enzyme Acetylcholinesterase to produce an overstimulation of muscarinic and nicotinic receptors present in the CNS, exocrine glands, hollow organs, among others. A narrative review was carried out based on keywords of poisoning, organophosphate, poison and acetylcholine in between 2015 and 2020. Organophosphate poisoning mainly presents in cholinergic syndrome product of overstimulation of the muscarinic receptors. Subacutely, it can present as intermediate syndrome and subsequent consists polyneuropathy induced by organophosphates. The clinical findings pesticide exposure will provide the diagnosis. In the driving initial symptomatic should use atropine, which will act in a competitive with ACh for muscarinic and nicotinic receptors, but the reversal of the action of the organophosphate on AChE is only carried out with the oximes, pradiloxime is the first choice. The reviewed provides updated information about key aspects in organophosphate poisoning as well as a approach in the clinical presentation.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.001 | 0.002 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".