Oral anticoagulants and the risk of an osteoporotic fracture among the elderly
Bibliographic record
Abstract
Background. Oral anticoagulants are associated with a decrease in bone mass density. Our study evaluates the association between an osteoporotic fracture and oral anticoagulants. Methods. We conducted a case-control study on subjects aged 70 years and older enrolled in the Quebec health insurance plan between 1992 and 1994. Incident cases of an osteoporotic fracture (index event) were identified by ICD-9 codes and surgical procedure codes. Exposure defined as one or more prescriptions of oral anticoagulants dispensed before the index event. Ten controls for each case, matched by age and date of index event, were selected. Results. Among 1,523 cases, 48 (3.2%) were exposed to oral an anticoagulant; among 15,205 controls, 461 (3.0%) were exposed (adjusted odds ratio: 1.1, 95% CI: 0.8--1.4). These negative results persisted after stratifying the exposure into the cumulative dose and duration of treatment. Conclusions. Oral anticoagulants are not significantly associated with an osteoporotic fracture in the elderly.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".